Esa-Pekka Pälvimäki (@eppe) header
Esa-Pekka Pälvimäki (@eppe) profile picture

MD Neurosurgeon | PhD Pharmacology. Developer. Fooled by randomness. Back on twitter because of A.I. If you suspect I'm wrong, see my pinned tweet

Helsinki, Finland
Joined December 2008
Photo by Esa-Pekka Pälvimäki (@eppe)Photo by Esa-Pekka Pälvimäki (@eppe)Photo by Esa-Pekka Pälvimäki (@eppe)Photo by Esa-Pekka Pälvimäki (@eppe)Photo by Esa-Pekka Pälvimäki (@eppe)Photo by Esa-Pekka Pälvimäki (@eppe)Photo by Esa-Pekka Pälvimäki (@eppe)Photo by Esa-Pekka Pälvimäki (@eppe)Photo by Esa-Pekka Pälvimäki (@eppe)Photo by Esa-Pekka Pälvimäki (@eppe)
Esa-Pekka Pälvimäki retweeted
Replying to @claudeai
All those years of refusing to learn Excel, Word and PowerPoint is about to pay off.
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Esa-Pekka Pälvimäki retweeted
I gave Fable 5.2 a PDF of one of Leonardo da Vinci’s 500-year-old notebooks and it made his inventions real for me to interact with. Such an exciting time for education. Anything from history that’s been stuck on a page can now be something you explore.
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Esa-Pekka Pälvimäki retweeted
If there is one thing the AI revolution has taught me, it’s that 99% of people cannot extrapolate. At all. Quite literally people cannot imagine or visualize progress or changes beyond the current state. Complete inability to predict the future.
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Esa-Pekka Pälvimäki retweeted
First evidence that AI does not behave like humans.
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Esa-Pekka Pälvimäki retweeted
Earlier this week Tristan published his top YouTube channels: thume.ca/2026/11/01/youtube-… Which looked excellent so clearly I had to turn it into TristanTube: karpathy.ai/tristan-tube/ 47K super nerdy videos +TV mode for laid back watching. (One-shotted with Claude Code in 3 minutes)
Weekend hack: HackerTube. I was annoyed with YouTube's recommendations so I had Claude filter down 43M comments over 20 years of HN to 6,454 videos that keep being recommended. *Significantly* better viewing experience, ~2 hours with Opus 5.5: hackertube.org/ - Excellent recs without any logins (state is kept in local browser session) - Thumbnail is a representative frame from middle of the video instead of the super duper A/B test hyper-optimized user uploads - Underlying data from the comment analysis as one zip file, point your Claude at it and ask for your own version - HackerTube Longs ✊ A bit more on the process: I use Claude Code (desktop app for Mac), Opus 5.5 on Medium effort as my default. I only talk to Claude and have it do everything, the only "manual work" I helped with in tandem was in the browser (reminiscent of MenuGen): 1) I had to create some kind of API key from Google Cloud UI to query YouTube for video metadata, 2) I booted up a VPS box for serving and 3) I bought the domain name. Once the box was up I gave Claude the IP and told it update, secure, harden, deploy and optimize the code, and it did the whole thing. Many awesome projects that would have normally taken weeks/months even can now be few-shotted for breakfast. What else are we not thinking of.
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Esa-Pekka Pälvimäki retweeted
Let me be blunt. Those who are afraid of AI feel deep down that they are impostors & have no edge. If you have a 1) clear mind, 2) a deep, not just cosmetic, undertanding of your specialty, 3) and/or are original enough to reinvent yourself when needed, AI will be your friend.
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Esa-Pekka Pälvimäki retweeted
Kudos to Gelje Sherpa for his heroic act! When faced with a choice between personal glory and a fellow climber's safety, he unhesitatingly rescued the Malaysian climber from the treacherous height of #Everest near Balcony (~8300 m). His act of courage shines as bright as the Himalayan sun. Video ©: Gelje Sherpa/IG.
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Esa-Pekka Pälvimäki retweeted
Scientists have recorded the coldest temperature ever measured in a lab. They attained a temperature of just 38 trillionths of a degree above -273.15 °C. This achievement made the laboratory the coldest place in the observable universe. The temperature reached is the closest..1/
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Esa-Pekka Pälvimäki retweeted
Utti Jaeger Regiment will command TREX #SouthernGriffin23 in Southern Finland 10–21 May. Among others, the exercise will be participated by international partners from the U.S.A. and Europe. maavoimat.fi/en/-/utti-jaege… #readiness #sof #finsof #utjr #StrongerTogether #finarmy
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Esa-Pekka Pälvimäki retweeted
"Ambition accounts for 50% of success. And 100% of failures." @nntaleb
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We are honoured to welcome 🇫🇮 #finland as the 31st member of the @NATO Alliance. The 🇫🇮 SOF bring highly trained & capable forces along with expertise in national resilience and years of experience working side by side with #NATO #SOF Allies. #WeAreNATO #StrongerTogether #utjr
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Esa-Pekka Pälvimäki retweeted
The perigee Moon captured behind a tree in the act of rising by photographer Bernd Nowack [Author's site: nowack.photo/]
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Esa-Pekka Pälvimäki retweeted
David Deutsch, Tim Ferriss, and Naval Ravikant — The Fabric of Reality And Much More youtu.be/FfWbcrObpUY
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Esa-Pekka Pälvimäki retweeted
Great residency, better department, best colleagues. Today I held my graduation speech #HelsinkiNeurosurgery
This Post is from an account that no longer exists. Learn more
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Esa-Pekka Pälvimäki retweeted
Utti Jaeger Regiment will arrange a bilateral exercise with the USA in Finland from 13 May to 5 June 2022. The exercise is part of the Finnish Defence Forces’ international training and exercise activities for 2022. maavoimat.fi/-/yhdysvaltalai… #utjr #finsof #finarmy #defencefinland
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Infusing young #CSF directly into aged brains improves memory function. Imagine what discoveries are on the way with #ActiveCSFexchange nature.com/articles/s41586-0…
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Esa-Pekka Pälvimäki retweeted
Replying to @dgurdasani1
The UK will have an epidemic of type 1 #diabetes in children because of failure to protect them. cdc.gov/mmwr/volumes/71/wr/m…
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Esa-Pekka Pälvimäki retweeted
The whole idea of the precautionary principle is to take inexpensive action early to mitigate the need to navigate multiple costly options later With covid the "precaution window" went out the door by March 2020 We are experiencing the mess of costly options now
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Esa-Pekka Pälvimäki retweeted
If you are thinking of improving your domain strategy, you've got to read this article by @AGreatDomain on name @NamePros. Bob did detailed analysis of tools that can help you up your game. namepros.com/blog/finding-te…
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Esa-Pekka Pälvimäki retweeted
BREAKING [Thread]: 1. SA’s first real-world data on #Pfizer’s #COVID19 jab’s protection @ #Omicron infection + hospitalisation via @Discovery_SA + @MRCza Note: This is data from the 1st 3 weeks of the outbreak, so it might change - regard it as preliminary real-world data
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