Technology to reduce suffering and create joy. Design/build molecules and machines.
@GeneChaser / CT / CO
Joined August 2010
- Tweets215
- Following474
- Followers144
- Likes445
Isaac Bean retweeted
1/7 Improving de novo Protein Binder Design with Deep Learning (biorxiv.org/content/10.1101/…) We show that AF2 is an effective predictor of whether a de novo designed miniprotein will bind to the intended target or not.
Isaac Bean retweeted
1/
Successful Public health Programs rely on Engineering principles as much as medical ones
It’s rare that public health is discussed with Engineering
But it should be.
Public Health Engineering Depts. should exist!
A wonderful article by @paimadhu
forbes.com/sites/madhukarpai…
So proud to have met @jensstoltenberg at the South Pole Station.
Thank you for leading the fight for light during these dark times.
Isaac Bean retweeted
Delighted to announce the publication of our work on *Microfluidic Chain Reaction* (MCR) in @Nature.
MCR help realize a true lab-on-a-chip and could perform medical tests. You may download, modify, and 3D print your own MCR chip 😎
rdcu.be/cNP7l
1/n
Isaac Bean retweeted
Ever wanted to turn on a gene with electricity? Our work on #synbio and #electrochemistry tools for electronic control of gene expression is out now in @ScienceAdvances! ⚡🦠 Here's a summary of our findings 🧵 science.org/doi/10.1126/scia… 1/11
Isaac Bean retweeted
Feels like style and design has traditionally been an afterthought in biotech (understandable given we’re making drugs prescribed by doctors), but perhaps that changes in an era of talent wars and new technologies.
Art, science, and entrepreneurship are each rooted in creation.
Isaac Bean retweeted
Start your new year at the Clyfford Still Museum! Explore the exhibition, A Decade of Discovery: Clyfford Still in Denver, and make discoveries!
Isaac Bean retweeted
E. coli consortium for biodegradation:
Artificial Consortium of Three E. coli BL21 Strains with Synergistic Functional Modules for Complete Phenanthrene Degradation
doi.org/10.1021/acssynbio.1c…
Isaac Bean retweeted
So live a life you will remember
Launched detect.com
Discovered #Omicron on @iontorrent
When thunder clouds start pouring down
WildFire, SBS, Zemax, hack like Woz or Python Pi
These are the nights that never die
email [email protected]
Thinking about a low cost easy to manufacture home test kit for #Coronavirus. Outline: #Nasal_swab (Q-tip) w/ freeze dried reagents for isothermal #DNA amplification with #COVID19 primers. Colorimetric readout by #iOS or #Android #App w/ #geolocation & #HIPPA compliant reporting.
Isaac Bean retweeted
If you can build & use equipment like @Craggs_Lab please come join us.
We are looking for single molecule talent. Molecular biologists, biophysicists, coders. Tenacious, Joyful, entrepreneurial.
[email protected]
Send TWO references to
[email protected]
Redo time:
Build your own smfBox - everything you need to build and run accurate and dynamic smFRET experiments - cheaply! #openAccess #openSource #openMicroscopy Paper here:
rdcu.be/b9Prx
And a great intro video here from the master of microscopy nightmares @DrLachie. Enjoy!
Isaac Bean retweeted
Intern with me. Land & Sea. Winter, spring, summer & fall.
Want first crack at starting the next @4Catalyzer company?
Do molecular biology & coding projects in one-third the time most competent people think possible?
Email CV & have references sent to [email protected]
Isaac Bean retweeted
FDA approved @DetectTest.
You you can order a PCR-quality test for home use THIS MORNING!!!
Detect.com
Thinking about a low cost easy to manufacture home test kit for #Coronavirus. Outline: #Nasal_swab (Q-tip) w/ freeze dried reagents for isothermal #DNA amplification with #COVID19 primers. Colorimetric readout by #iOS or #Android #App w/ #geolocation & #HIPPA compliant reporting.
Isaac Bean retweeted
“But biological design will not be limited to steel tanks forever. What do we want to do after fermentation?”
“Until we can comprehend the majority of eukaryotic life, we are playing in the shallows of an ocean of biological potential.”
Do yourself a favor and read @davian_ho on protists and what they could mean for a future synthetic biology. @JourneyToMicro
growbyginkgo.com/2021/12/13/…
Isaac Bean retweeted
"Around the world, scientist and entrepreneurs are integrating abundant renewable energy, more powerful batteries, breakthroughs in fields like synthetic biology, to invent a better future that is healthier and more affordable." - @BarackObama
youtube.com/watch?v=D2ScHyXs…
Isaac Bean retweeted
A look at #syntheticbiology’s embodiment and advancement of equity, humility, sustainability and solidarity over time. #synbio @wef
Revisiting and Realizing the Promises of Synthetic Biology | World Economic Forum bit.ly/3pYiBQC
Isaac Bean retweeted
My first release of #Jupyter_Dock: Molecular Docking integrated in Jupyter Notebooks (Git repo: bit.ly/3zmCZvU)
Notebooks for:
- Molecular Docking
- Virtual Screening
- Blind Docking
- Reverse Docking
- Docking Analysis
Example:
bit.ly/2Z1KtYC
#compchem
Isaac Bean retweeted
We are living through a renaissance in the field of computational protein science. This has enormous implications for biotechnology at large. Check out my COB highlight of the amazing recent work from @UWproteindesign on protein binders:
centuryofbio.substack.com/p/…
Isaac Bean retweeted
Today marks the 25th anniversary of Neil Risch and Kathleen Merikangas' classic 2-page paper that articulated GWAS as the future of human genetics. A short thread.
www-leland.stanford.edu/~hua…
