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I am pleased to share our review on "Cause, Epidemiology, and Histology of Polyps and Pathways to Colorectal Cancer". Thank you to authors @gi_sullivan and @nouji87 and to editor @AasmaShaukatMD. #coloncancer #GITwitter @Duke_GI_ authors.elsevier.com/a/1edb0…
Jatin Roper retweeted
This is great news. What a relief. Judy is an awesome scientist and a great leader. NHGRI is in good hands.
NEWS: NIH selects Dr. Judy Cho as director of the National Human Genome Research Institute.
Read the full story ➡️ bit.ly/3U4Jsvr
Jatin Roper retweeted
This study changed the way I think about cachexia. For a long time we have been looking for tumor-secreted factors that induce sickness and wasting. @ThalesPapaG now shows us that the "sickness signal" can be transmitted directly to the brain via sensory neurons. Congrats to the whole team. #CANCAN @CancerGrand @theNCI @CRUKresearch
science.org/doi/10.1126/scie…
Jatin Roper retweeted
The National Cancer Institute mourns the loss of Joseph F. Fraumeni, Jr., M.D., pioneering cancer epidemiologist and founder of NCI’s Division of Cancer Epidemiology and Genetics. His work transformed cancer research worldwide. We extend our deepest condolences to his loved ones.
Jatin Roper retweeted
Independent analyses estimate that your actions to dismantle USAID and drastically reduce lifesaving foreign aid have already killed 700,000 people. Here are some of those people. 🧵xitter.cf/elonmusk/status/206944…
All DOGE required was contact information of the recipients to confirm that funding was not fraudulent. No validated medical funding was stopped.
Anything that appeared to be legitimate lifesaving funding continued and is now administered by the State Department.
If anyone had actually died as a result of DOGE, their names would be worldwide headline news!
On the other hand, USAID did help fund the Wuhan Virology Institute, which caused the deaths of millions, and the revolution that started the Russia-Ukraine war.
LCongratulations to Roper Lab undergraduate students Vyom Patel and Sahil Choudhri on completing their senior honors theses.
Pharmaceutical giant Roche announced it is launching a new large-scale “AI factory” with thousands of the latest Nvidia chips to accelerate the development of new drugs and diagnostics.
Roche said the company has ramped up its AI capacity by purchasing 2,176 Nvidia Blackwell GPUs, which will be deployed across the U.S. and Europe.
That brings its total GPUs to more than 3,500, which it claims is the greatest number owned by any pharmaceutical company.
Roche, which made the announcement in conjunction with Nvidia’s GTC conference in San Jose, hopes to use that technological firepower to discover, develop, manufacture and commercialize therapies faster.
Learn more: forbes.com/sites/amyfeldman/… (📸: Richard Morgenstein 2021)
Duke researchers study why some colorectal liver metastases respond to chemo, in an effort to better personalize care.
“We’re excited to contribute something new that has the potential to change how we approach treatment.”-Dr Nicholas DeVito
#ColorectalCancerAwarenessMonth
A team at DCI is launching a first-of-its-kind study that could bring new hope to patients living with advanced #ColorectalCancer.
duke.is/w/r2hv
@DukeMedSchool | @DukeSurgery | @DukeEngineering
🌟Congrats, to @KWegermann and team!
Triglyceride and ceramide metabolites associate with MASLD in people with HIV. Excited to be at my first @CROI_Official! Thanks @AmCollegeGastro for funding my work! @snaggie1 @CindyMoylan_MD
Jatin Roper retweeted
A new study published in @Nature by researchers at MSK, led by @TuomasTammela, shows that a small number of highly plastic cancer cells drive cancer progression and the ability to evolve resistance to treatment. Learn more: bit.ly/4bmG1a5
Managing Patients With Colorectal Liver Metastases - CME with @DukeHealth
This brief accredited #CME activity reviews how to evaluate patients with metastatic colorectal cancer to the liver and select an appropriate treatment strategy.
Explore the CME ➡️ duke.is/r/87y3
@DukeCancer @michael_lidsky
Jatin Roper retweeted
👏Congratulations to Reuben Cano with the @Duke_GI_ Jatin Roper Lab for receiving a 2025 Student Traineeship Award from @CF_Foundation
We're excited to see the discoveries that lie ahead!
#FutureOfMedicine #CysticFibrosis #GIGoodNews #GIResearch #CFF
Jatin Roper retweeted
Drumroll... 🥁We’re thrilled to announce our 2026 GI Fellowship Match! Five incredible Duke IM residents will join the Duke GI Family in July!
Welcome to the team! 💙
#Match2026 #FutureOfGI #DukeFam #GIFellows #GITwitter #FellowMatch #DukeFamily #GIGoodNews
Jatin Roper retweeted
🤩🤩Excited to virtually host (with @AndrewBerchuck and our #geneticcounselors) the international #hereditarycancer expert @judygarber5 from @DFCI_BreastOnc at our inaugural @DukeCancer Clinical Cancer Genetics Signature Speaker Series! Fantastic presentation!!👏👏👏
Jatin Roper retweeted
This week is Crohn’s & Colitis Awareness Week.
🟣 Nearly 3M Americans live with IBD conditions, often invisible but certainly life-changing.
🟣Join Duke GI in raising awareness & supporting all affected.
💜 #IBDAwareness #IBDLooksLike #CrohnsAndColitisAwarenessWeek #IBDVisible
Jatin Roper retweeted
Today I turn 55.
I’m the fittest, sharpest, and happiest I’ve ever been.
If I’m an outlier, it’s not because I’m built different or discovered a secret formula. The truth is far less glamorous:
It’s a million tiny choices, compounded over decades.
Here are 55 of them:
1. Walk 15+ miles a week, even if you do other exercise. Humans are uniquely made to move slowly over long distances—it’s critical to longevity.
2. Develop a writing practice. It’s the single best way to sharpen your mind. And remember, you don’t have to be a good writer to write. Start with 10 minutes a day.
3. Swap out your toothpaste, deodorant, lotions, soap, shampoo, and other personal care products for natural versions. Here’s a rule of thumb: Don’t put anything on your skin that you couldn’t safely eat.
4. If you have a positive thought about someone, don’t keep it to yourself—share it immediately. Encouragement defies the laws of physics: When you give energy, you also receive it.
5. Wear shoes with a wide forefoot (I like Topo Athletic) and wear toe spreaders around the house (search “yoga toes” on Amazon). Spine health begins with the feet.
6. Get sunlight regularly. Moderate sun exposure (without sunscreen) is hugely important for overall health.
7. Do a 3-minute deep (“ass to grass”) squat every morning. Deep squats are often called the anti-aging exercise. It’s been said that, “It’s not that you can’t do deep squats because you’re old, it’s that you’re old because you can’t do deep squats.”
8. Explore minimalism (it’s not what you think it is).
9. Set boundaries on toxic relationships. We tend to cling to relationships past their expiration date, and it takes a bigger toll on our health than we recognize.
10. Eat real food. Not too much. Don’t eat garbage. Binge occasionally. Fast occasionally. That’s the diet.
11. Learn about FIRE. It’s a great framework for financial success.
12. Don’t take antibiotics except in emergency situations. They’re massively over-prescribed and aren’t needed in most cases. Antibiotics have done untold damage to our guts, which is where health begins. Great natural alternatives are out there.
13. Get 8 hours of quality sleep each night. To optimize sleep:
—Don’t eat after 6pm
—Get blackout shades and cover LEDs with black tape
—No screens 2 hours before bed
—Try ashwagandha (an herb) to calm the nervous system
14. Stop drinking, even in moderation. People find all sorts of ways to justify drinking, but there’s no escaping the simple fact that alcohol is a toxin and it limits your potential.
15. Travel as much as possible. Nothing expands the mind like seeing the world. And travel doesn’t have to be expensive—the best experiences happen outside of fancy resorts, when you live like a local.
16. Let go of resentment. When you forgive someone, you release the prisoner, and the prisoner isn’t them… it’s you.
17. Show up on time, every time. Poor time management limits success more than most people realize. If you struggle with punctuality, stop everything else and fix that first.
18. Spend lots of time in nature and touch the earth. Humans evolved over 300k years to live in harmony with nature, and only recently have we retreated indoors. If you don’t spend time outside, you’re fighting biology (hint: You won’t win.)
19. Stop doing dumb things. As Leo Tolstoy said, “People try to do all sorts of clever and difficult things to improve life instead of doing the simplest, easiest thing—refusing to participate in activities that make life bad.”
20. Find your happy place and (eventually) move there. Most people live where they live because... that's where they live. We are products of our environment—choose yours carefully.
21. Find a hobby and pursue mastery. You can’t have a happy life without a passionate pursuit that isn’t your vocation. Your work—even if you enjoy it—isn’t enough.
22. Avoid mainstream medicine except as a last resort. The results are in—our healthcare (or more appropriately, sick care) system is badly broken and only makes people sicker.
23. Have a mindset of abundance. There is no advantage to being a pessimist—even if you’re right, it’s a miserable way to live. In a very real way… whatever you believe, you’re right!
24. Do hard things. Choose courage over comfort. Everything you want is on the other side of fear and hard work. As Jerzy Gregorik said, “Hard choices, easy life. Easy choices, hard life.”
25. Ignore haters. Hurt people hurt people. Negative/toxic people live in a prison of their own design. Don’t join them!
26. Say no. Protect your time and energy like it’s your most precious asset… because it is.
27. Become a water snob. As an alien said on Star Trek, humans are “ugly bags of mostly water.” You are what you drink—literally! We have Mountain Valley Spring water delivered in glass 5-gallon jugs and also have whole-house water filter (Aquasana Rhino).
28. Stop drinking sodas and sugary energy drinks. After a few weeks you won’t miss them, and a few months later they’ll seem disgusting. Refined sugar causes inflammation, which is the root of most disease.
29. If you’re over 35, find a good functional/longevity medicine doctor and start tracking your hormones. Modern life is hell on the endocrine system and restoring healthy hormone levels can change your life. As we get older, we either accept a slow decline in performance or we do something about it—choose the latter!
30. Develop a morning routine and follow it faithfully. Win the morning, win the day!
31. Invest in experiences, not things. People frequently regret buying things, but rarely regret investing in great experiences (especially when shared with loved ones). Remember, there’s nothing you can buy in a mall that you’ll remember in ten years.
32. Explore spirituality. It’s arrogant and small-minded to believe there’s nothing going on in our universe that is beyond our comprehension. We know less about our universe than an ant meandering on a sidewalk understands about this planet.
33. Have a strong bias toward action—doing rather than talking. If you ask a bunch of old people about their regrets, they’ll talk about the things they *didn't* do—the shots they didn’t take—more than the things they did do (even if it went wrong). As Wayne Gretzky famously said, “You miss 100% of the shots you don’t take.” Most people don’t take enough shots.
34. Stay lean. Men in particular are obsessed with muscle mass these days, but bulk doesn’t age well. The goal is to be strong but lean. The fittest guys in their 50s and beyond aren’t meatheads, they’re lean guys who are serious about a sport.
35. Curate your inner circle carefully. Surround yourself with people you admire and who challenge you to grow. Remember, we’re the average of our 5 closest relationships.
36. Be the fittest version of yourself. Your body is your only vessel for experiencing life—so treat it as such. Fitness isn’t working out a few times a week, it’s a lifestyle. The older you get, the more time you need to devote to your health.
37. Take the time to appreciate art and beauty in all its forms.
38. Think globally, but act locally. Too many people put their energy into far-away problems they don’t understand and can’t impact, while ignoring problems right under their nose. Want to change the world? Start at home.
39. Try psychedelics. It’s one of those things everyone should do at least once, and it might be the breakthrough you’ve been looking for.
40. Limit bad habits, including unhealthy thought patterns. We all have them—practice avoidance and find substitutes. Get professional help if needed.
41. Be a lifelong learner. Your brain is just like a muscle—if you don’t feed and flex it regularly, it will atrophy.
42. Find your purpose. People with a strong sense of purpose are happier and live longer. Lack of purpose sucks energy and magnifies depression.
43. Only take advice from people who embody the traits you want to have. Talk is cheap—emulate those who have DONE it.
44. The goal is not to retire and do nothing, it’s to build a great day-to-day life that you don’t need to escape. A life of leisure is a slow death. Happiness isn’t possible without a little struggle, uncertainty, and skin in the game.
45. Have fun! Do frivolous and silly things that make you smile. As George Bernard Shaw famously said, “We don't stop playing because we grow old; we grow old because we stop playing.”
46. Whatever you want to do or achieve in life, start NOW. Don’t fall victim to “someday thinking” because someday never comes.
47. Accumulate assets—things that grow in value over time. It’s the #1 habit of rich people, and it can be done in tiny chunks. Instead of spending $100 on an impulse purchase that has no lasting value, put that money into an index fund or Bitcoin. It becomes addictive (in a good way).
48. Don’t ignore the big 3 canaries in the coal mine for health:
—Low libido (and ED)
—Frequent sinus & respiratory issues
—Depression
These usually aren’t medical conditions in themselves, they’re symptoms of an underlying problem. Find a good doc (outside of the mainstream) and figure out the root cause.
49. Have a clear vision for your future. How can you decide which direction to go if you haven’t clearly defined the destination? It sounds obvious, but 95% of people haven’t defined their “Ideal End State” in detail and in writing. (Check out my thread on this topic.)
50. Make your own decisions. We live in an era where most of what society tells us is wrong. Don’t be afraid to break from societal norms—if people say you’re crazy, it’s a sign that you’re doing something right.
51. Get hardcore about mobility exercise. As you age, it’s usually the knees, hips, and lower back that limit physical performance. 30 min a couple times a week can spare you a lifetime of pain. YouTube is a great resource.
52. Go all in on family. Get married, stay married, have kids. Burn the boats. In the end, family is all that matters.
53. Be ruthless with your time. Money comes and goes. Time only goes. Audit your calendar ruthlessly—cut the trivial, double down on the meaningful, and spend your hours like your life depends on it. (Because it does.)
54. Have a strong bias toward action. Be curious, try things, meet people—it’s how you increase your surface area for serendipity, the most powerful unseen force in our lives.
55. Reinvent yourself every decade. Over time, we slowly drift off course from our priorities, values, and true identity. Take stock and don’t be afraid to hit the reset button. Bold, calculated moves made for the right reasons almost always pay off—usually even more than you can imagine.
🎁 P.S. If you enjoyed this post, would you give me a birthday gift? Repost or comment with the item number(s) you liked best?
Jatin Roper retweeted
When you bring the squad AND the science! Duke GI dominating Research Day. 🏆 #PosterGoals #GIResearch
Jatin Roper retweeted
Little late but wanted to acknowledge these 🤩 amazing @DukeCancer #GeneticCounselors for GC Awareness Day!! 🔥 Fabulous team providing 🌟 outstanding care for our patients and community!! 🙏 Thank you for all you do!!
Jatin Roper retweeted
📔New case report from Dr. Jatin Roper presents a rare instance of exercise-induced colon ischemia in a healthy middle-aged female and successful implementation of a novel therapeutic approach.
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