Absolute binf. Director @fulcrumgenomics. Solely responsible for my own hot takes.
Livermore, CA
Joined April 2009
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John Didion, PhD (🧬/🦀) retweeted
Sometimes I find it helpful to assume (at least for the next 10 mins) that the LLMs will tell you what the informed person will tell you not the expert who will challenge conventional wisdom. For things I am an expert on and can think creatively about, I see them make the same mistakes as those who would over-rely on consensus opinions of the well informed but non-rigorous. Currently, they can be pushed in this direction but you have to know where to push
John Didion, PhD (🧬/🦀) retweeted
There's a font used just about everywhere — on road signs, elevator buttons, and old computer keyboards — that has no "official" name. You've probably seen it hundreds of times without realizing.
Its origins can be traced back to an obscure Wisconsin machine shop. A great blog🔻
John Didion, PhD (🧬/🦀) retweeted
Thrilled to be launching @terrainbiosci today!
Revolutionizing RNA medicines with our AI-powered design & manufacturing platform
Helping biotechs get better mRNA candidates to patients, faster 🧬 #biotech #RNAmedicine
w/ @jgooten @pdhsu Chetan and many others (awesome team!)
Terrain Biosciences, backed by high-profile players in biotech, will design and supply RNA molecules for new therapies. trib.al/swyJBbA
John Didion, PhD (🧬/🦀) retweeted
Type annotation in Python is all of the work of writing in a statically-typed language with zero of the benefits. I really don't get it.
John Didion, PhD (🧬/🦀) retweeted
There ARE inter-individual differences in all sorts of traits - including immune responses - but these are best characterized at the level of the individual not at the level of groups - and given our ability to characterize individual genetics and physiology it is madness in nearly all cases to continue to use continental ancestry as the basis for scientific inquiry or medical treatment.
Setting aside that this is one of those worthless interview questions that depends on the interviewee having memorized a formula…
Phil Karlton famously said naming things is one of the two hardest problems in CS. Kai fails for sucking at naming.
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John Didion, PhD (🧬/🦀) retweeted
In which a comedian accurately describes the deindustrialization of the U.S. via its global dollar structure better than most macro analysts:
John Didion, PhD (🧬/🦀) retweeted
NIH will eliminate embargo periods at the end to 2025.
Author Accepted Manuscripts will be publicly available in PubMed Central without an embargo. grants.nih.gov/grants/guide/…
John Didion, PhD (🧬/🦀) retweeted
Bay Area Winery meetup was delightful! And this is not the last one of the year! More meetups coming up before the holidays 🧬✨
John Didion, PhD (🧬/🦀) retweeted
Our last of the year Bay Area meetup will be happening at a winery in the East Bay, accompanied with live music and food trucks! Please sign up if you can make it as spots will be limited for this one lu.ma/zijmv8mk
John Didion, PhD (🧬/🦀) retweeted
Making HQH happen at the last @TechBi0 meetup in the Bay Area on Dec 6 🍷🧬
Our last of the year Bay Area meetup will be happening at a winery in the East Bay, accompanied with live music and food trucks! Please sign up if you can make it as spots will be limited for this one lu.ma/zijmv8mk
Ok I’ll eat my words a bit…OneRepublic is not my kinda music but the less singer is obviously really talented. Enjoying the show despite my prejudices. Thanks @PacBio
John Didion, PhD (🧬/🦀) retweeted
Benchtop HiFi: PacBio Unveils Vega
🧬🖥️
omicsomics.blogspot.com/2024…
I'll be there with my #Rust -colored glasses! Send me a DM if you'd like to meet up.
John Didion and Tim Fennell from the Fulcrum Genomics LLC team will be at #ASHG2024 in Denver from November 5-9. Drop us a line if you’d like to connect in person!
#ASHG24 #HumanGenetics #Bioinformatics #Genomics #NGS
John Didion, PhD (🧬/🦀) retweeted
After nearly six months waiting for review, our extension to vcfdist was finally published in BMC Genome Biology this week!
genomebiology.biomedcentral.…
