Computational biology and aging
Bellinzona, Switzerland
Joined December 2012
- Tweets260
- Following586
- Followers565
- Likes423
Kevin Perez retweeted
NEW STUDY: Ocampo Lab publishes reprogramming cocktails that reduce DNA damage & extend lifespan of worms up to 42%.
The race is on to test them in humans 🚀
Kevin Perez retweeted
Excited to share our new publication! We previously showed that age reversal can be achieved using transcription factor-based reprogramming. Now, we demonstrate that it can also be done with chemical cocktails to achieve lifespan extension!
embopress.org/doi/full/10.10…
Kevin Perez retweeted
0/ It sounds wild, but low-dose Cialis (tadalafil) and Viagra (sildenafil) are both drawing attention for longevity benefits.
Recent clinical evidence indicates the use of either correlates to longer survival in men, in addition to their potential for heart health, metabolism, and even brain function.
A new retrospective study evaluated the longevity potential of 407 prescription drugs in over 200,000 participants, with both Cialis and Viagra being among the surprising promising hits in men (yet to be evaluated in women, since the retrospective studies only cover existing drug use for established indications).
Sildenafil will soon be tested in the NIA’s ITP, the most credible pre-clinical longevity drug testing program in mice.
Kevin Perez retweeted
@ZelarCity's final summit is this weekend and I’m incredibly proud and in awe of what we've co-created over these 6 weeks.
We’re bringing together some of the brightest minds pushing the boundaries of what's possible in longevity and we’re thrilled to announce that @geochurch, a true pioneer in genetics and synthetic biology, will be sharing his insights.
This is a rare opportunity to hear directly from one of the leading visionaries in the field.
Don’t miss it. Sign up here 👇
lnkd.in/dZWTCTsh
A big shout-out to my incredible team for their hard work and dedication: @longevion
@strygah @EliasSchlie @ElenaMishina15 @ZivaPecjak and everyone contributing. You rock!
Kevin Perez retweeted
Four common medicines, including Viagra and HRT, appear to have life-extending effects. newscientist.com/article/242…
Kevin Perez retweeted
Can Viagra, SGLT2 inhibitors, and estrogen be used as geroprotectors?
Recent #preprint suggests those and 11 other drugs are associated with decreased mortality risk in humans.
lifespan.io/news/study-sugge…
by @ArkadyMazin
@aocampox @epiterna_ @OcampoLab @kgiperez @RollandYves2
Kevin Perez retweeted
20 years ago, scientists figured out how to make mice live 150% longer by altering one singular gene. What have we learned since this groundbreaking discovery?
In our debut video, @alexkesin seeks to find out.
Kevin Perez retweeted
Help save the Dog Aging Project.
Despite being one of the most influential, productive and impactful NIH supported projects over the past 5 years, the National Institute on Aging has inexplicably chosen to withdraw support for the Dog Aging Project. For now, I’m won't get into the details of the process or my personal feelings about it, as the important thing is to ensure the Dog Aging Project doesn’t end. If you believe that the Dog Aging Project has value and should continue, I have three requests of you:
(1) Please consider signing the petition to the NIH Director here: actionnetwork.org/petitions/…
(2) Please consider sending an email to your elected representatives here: actionnetwork.org/letters/su…
(3) Please share this message with your network as broadly as you can
Thank you!!!
Kevin Perez retweeted
Twitter help! In line with my previous tweet, what private companies do you know that are testing drugs to evaluate their effect on the lifespan of animals? Testing might include large screenings, lifespan assays, work as CRO, preclinical studies, clinical trials. Please retweet!
Kevin Perez retweeted
In my opinion, most clinical trials for the treatment of age-associated diseases by targeting fundamental mechanisms of aging will unfortunately fail! Although aging is the major risk factor for these diseases, it will be very difficult to treat them rather than prevent them!
Kevin Perez retweeted
An image is worth a thousand words! Drug discovery of lifespan extending interventions at large scale. Lifespan data generated at @epiterna_
epiterna.substack.com/p/revo…
Kevin Perez retweeted
This report is the months-long culmination of some of the brightest young leaders in the longevity field coming together to prioritize and detail the field’s top bottlenecks:
amaranth.foundation/bottlene…
Kevin Perez retweeted
Wow, wow, wow!
In SELECT trial of patients with obesity (mean BMI 33, n>17,000) & prior atherosclerotic cardiovascular disease (but no diabetes),
GLP-1 agonist semaglutide 2.4mg once-weekly
reduced risk of CV death, heart attack, or stroke (RRR 20%)
novonordisk.com/content/nnco…
Kevin Perez retweeted
The Aging field was founded on studies showing discrete perturbations could increase lifespan in model organisms. Then one or two famous people performed perturbations that didn't result in lifespan-extension, and thus "healthspan" was invented.
Kevin Perez retweeted
Maybe I shouldn’t have published this one, but quoting Pontius Pilate… What I have written, I have written.
stanete.com/history-longevit…
Kevin Perez retweeted
Swiss #longevity company @epiterna_ exits stealth to tackle #aging
Using unique high-throughput drug screening platform, Epiterna aims to create ‘more time that matters’ for people & their pets.
#investment #economy #healthspan
longevity.technology/news/sw…
Kevin Perez retweeted
Today the @PrimaMateria_ team shares our third company: @EPITERNA_ which leverages life-extending science to create more time for pets and people.
We started Prima Materia to partner with some of the amazing scientists and engineers in Europe like @aocampox to build great technology companies together, so I’m really excited about this one!
epiterna.com/news/create-mor…
Kevin Perez retweeted
We’re excited to share our third company: @epiterna_ is leveraging life-extending science to create more time for pets and people.
We are excited to announce EPITERNA. Using a unique high-throughput drug screening platform, EPITERNA is leveraging evidence-based science to create more time that matters for people and their pets. epiterna.com/news/create-mor…
Kevin Perez retweeted
Swiss startup Epiterna has raised €10m from the Spotify founder's investment firm to develop drugs to combat the effects of ageing sifted.eu/articles/prima-mat…
Kevin Perez retweeted
We are excited to announce EPITERNA. Using a unique high-throughput drug screening platform, EPITERNA is leveraging evidence-based science to create more time that matters for people and their pets. epiterna.com/news/create-mor…