Structural Heart Interventional Cardiologist @UCHealth. Husband & father. Views my own. Alumnus: @BrownUniversity @UToledoMed @BIDMC_IM @BIDMCVFellows
Longmont, Colorado
Joined September 2008
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Mark Tuttle, MD retweeted
NIH has issued ~65% fewer (796 vs. 2300) new grants so far this year compared to the same point in prior years.
Combined with the delayed release of already-appropriated funding and we are witnessing unbelievable real-time damage to the U.S. scientific enterprise.
Mark Tuttle, MD retweeted
Chronic stent recoil occurred in 1 of 5 lesions treated with second- or newer-generation #DES requiring repeat #revasc, with severe calcium and nonuniform stent expansion identified as risk factors, and was associated with TLR. jacc.org/doi/10.1016/j.jcin.… #JACCINT #OCT
Mark Tuttle, MD retweeted
The 10 most striking Kaplan-Meier curves (that I have seen) 🧵
1. Dual GLP1/GIP agonist, Tirzepatide, for prevention of type 2 diabetes in people with obesity
It's easy to miss the dark blue line (15 mg group), because it never leaves the X axis:
Mark Tuttle, MD retweeted
On the day of #TCT_ME_ travel. 81-year-old female with very small annular size & area of 282 mm2 + little calcification!
Treated with 23 Evolut FX plus with mean gradient dropped from 52 to 3 mmHg & no PVL
Typical SMART trial patient
Testament to the power of SE technology
Mark Tuttle, MD retweeted
Welcome thoughtful National Coverage Analysis on #TTVR published yesterday. Access to healthcare is critical and @CMSGov decision is a testament. Great job! Treatment for TR enters a new era! @SCAI @ACCinTouch cms.gov/medicare-coverage-da…
Mark Tuttle, MD retweeted
Congrats to Howard Herrmann, @Drroxmehran @didier_tchetche and #SMART trial investigators for outstanding 2y data and outcomes #CRT2025, with excellent clinical and echo follow up! While no differences in hard endpoints (no surprise), what struck me the most is the adjudicated prosthetic valve thrombosis differences (clinical, subclinical) between #Evolut and #Sapien3 #TAVR, despite no differences (yet) in reintervention. But it reaffirms to us that BVD no matter how it’s defined is not a good thing for prosthetic valves, whether it’s TAVR or in the latest @JACCJournals paper by @StevenYakubov et al, SAVR. @MDT_StructHeart
Mark Tuttle, MD retweeted
Cutting NIH to save budget is like cutting the front lobe of brain to lose weight. It’s <1% of body weight yet it governs reasoning and problem solving functions of the brain, basically determining how smart you are. Dumb move to send IT kids to do your brain surgery, America.
Mark Tuttle, MD retweeted
Back to ECMO here in @GaHeart_NGHS and love it. Here’s why a retro perfusion cannula (that I started in @cusm_muhc) is better than an antegrade (see below)
Mark Tuttle, MD retweeted
"In interventional cardiology we will use the metric system to measure things."
"Like catheter diameters Sir?"
"No - those we will measure using French sizes."
"What about wires Sir?"
"We will measure those in inches"
"Why Sir?"
"No one knows"
Mark Tuttle, MD retweeted
Wow! Practice changing EARLY TAVR RCT. For a long time, we waited for aortic stenosis patients to become symptomatic before considering therapy, based on old data (risk of surgery vs watchful waiting). ASYMPTOMATIC patients with severe AS, TAVR leads to a major reduction in MACE with a NNT of just 6. #TCT2024
Mark Tuttle, MD retweeted
1. See patient in acute pain
2. Prescribe pain medicine so they can avoid the ER
3. Patient goes to pharmacy, is told that pain medicine requires prior authorization by insurer (who gave no forewarning of such and will not reopen til next day)
4. Patient ends up in ER anyway
Mark Tuttle, MD retweeted
Congrats to @BIDMCNursing Eric Harrington RN, Nate Masterson RN, @kim_guibone, and #BIDMC Alexanndra Murphy, RT, who were selected to present on "Nurse Led Sedation for TAVR" @ the @ACCinTouch Quality Summit!
