Pete Hendrickson (@pghendrickson) header
Pete Hendrickson (@pghendrickson) profile picture

Radiation oncologist @DukeRadOnc| DUX factors, embryonic genome activation, and cancer

Durham, NC
Joined May 2015
Photo by Pete Hendrickson (@pghendrickson)Photo by Pete Hendrickson (@pghendrickson)Photo by Pete Hendrickson (@pghendrickson)Photo by Pete Hendrickson (@pghendrickson)Photo by Pete Hendrickson (@pghendrickson)Photo by Pete Hendrickson (@pghendrickson)Photo by Pete Hendrickson (@pghendrickson)Photo by Pete Hendrickson (@pghendrickson)Photo by Pete Hendrickson (@pghendrickson)
The aggressive cancer cells featured in this image are undergoing cell death because of a selective inhibitor: doi.org/10.1172/JCI202218 Here, David G. Kirsch @DKirschMDPhD, Pete Hendrickson @pghendrickson & team @UofT & @DukeHealth establish a next-generation mouse model and identify Minnelide as a potential treatment for CIC::DUX4 #sarcoma, a rare and deadly cancer with no treatment options. @DukeRadOnc @pmcancercentre #CDS
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Just in time for #CTOS2024: Thrilled to share SU2C-SARC032 (NCT03092323), a randomized trial of pembrolizumab in Stage 3 extremity soft tissue sarcoma, now published @TheLancet! authors.elsevier.com/a/1k5Jb… 1/13 @SARCtrials @SU2C @ctosociety @RadMedPM @pmcancercentre @UHN @UofTDRO
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Pete Hendrickson retweeted
Your donation dollars in action! 🙌A #StandUpToCancer-funded #research team unveiled an exciting #clinicaltrial breakthrough that reduces risk of #cancer relapse by 43% – for 2 of the most common types of soft tissue #sarcoma in adults, 2 years after treatment. Learn more: bit.ly/4bH9BEI.
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Excited to share our work on chromatin landscape remodeling in cloned embryos! 🐄🐄We started off w/ simple question: how does the somatic epigenome reprogram to prepare for the onset of transcription (EGA)? tinyurl.com/yc4wv76p
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Pete Hendrickson retweeted
(1/5) Our paper on pooled genetic screening of TERT-mutated #glioblastoma is out in @NaturePortfolio @oncogenejournal! We analyzed data from 500 #clinical and ~1300 #preclinical samples. Graphical abstract in the thread! nature.com/articles/s41388-0…
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Pete Hendrickson retweeted
ROI 5k duke crew! #astro2023
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Physician-scientists are a dying breed going from 4.7% in '80s to ~1.5% today. Multiple factors contribute including flat/declining #NIH funding. Translational research is critical for advancing clinical care. jamanetwork.com/journals/jam…
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In SLC for Brad Cairns’ 25th lab anniversary. Was truly a humbling experience to be a part of great science with great scientists. We’ve spanned the gamut from biochemistry of yeast chromatin remodelers, zebrafish epigenome reprogramming, ZGA, and germline stem cells.
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Very impressive work! What compensates Dux in mouse ZGA has puzzled me for ~4 years. I generated Obox1/2/5/7 QKO, but failed to see apparent phenotypes. It turns out that Obox4 is the promising one! A big mystery is largely resolved! biorxiv.org/content/10.1101/…
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Competition for H2A.Z between genes and repetitive elements establishes response to anti-viral immune activation biorxiv.org/cgi/content/shor… #biorxiv_genomic
Thrilled to announce I've started a lab @UTSWNews studying epigenomics of oogenesis & early embryo development! Together, let's find out how to build eggs🥚 and embryos. Thanks to generous funding from @CPRITTexas we are recruiting @ all levels: utswgrowlab.com plz RT
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Congrats to Duke #RadOnc residents Alex Gooding, MD, PhD, and Peter Hendrickson, MD, PhD, who were recently inducted into @DukeMedSchool's Lefkowitz Society! The Lefkowitz Society is for MD and MD/PhD post-graduate trainees/those with the goal of becoming physician-investigators
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Meet our 1st #RadOnc Research Scholar! PGY3 Pete Hendrickson, MD, PhD, attended @UofUMedicine before coming to Duke. He’s an outdoor enthusiast & loves skiing, golfing, running and hockey (and his dog, Ryman!) radonc.duke.edu/faculty/pete… #MedStudents #MedStudentTwitter @pghendrickson
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A new $7.15 million gift from the Nanaline H. Duke Fund will help the School of Medicine continue to support early-career physician-scientists through the Strong Start program. bit.ly/3okWZd9 @DukeRadOnc @dukemedicine @DukeOPSD
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Duke PGY2 @pghendy is our #RadOnc Research Scholar. Why did he choose Duke? In his words, it offered "the most direct path to an independent lab & research-focused academic job in the country." Excited to see his accomplishments in the next few years! #MedEd #MedStudentTwitter
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Calling all #MedStudents – learn what makes Duke #RadOnc and @DukeCancer great at one of our resident-hosted virtual hangouts! Sign up to receive Zoom info at forms.gle/t5u1TTDei47F9LJX7 🔬 #MedStudentTwitter #MedEd #MedTwitter #RadOncRes #RadRes
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Pete Hendrickson retweeted
Just published @TheLancet The largest study of hydroxychloroquine shows a significant increase in death (~35%) and >2-fold increase of serious heart arrhythmias. ~96,000 patients, ~15,000 on HCQ or CQ from 671 hospitals, 6 continents. marlin-prod.literatumonline.…
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Molecular Targeted Radiosensitizers Preprint Intro osf.io/k9bfx/ 2020 @SpringerNature Iris Eke @StanfordRadOnc & I @MGHCancerCenter thank all authors incl collaborators @_MichaelBaumann @StevenLin_MDPhD @UMichRadOnc🙏 #radonc #RTdrugcombo #Oncoalert @NCIResearchCtr
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Pete Hendrickson retweeted
The two most common causes of hardship in PhD students are an inability to accept failure and choosing this career path for the prestige, rather than out of any real interest in research. go.nature.com/2IYZX4N
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