Cambridge, England
Joined October 2017
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Reg Myers retweeted
Everyone thinks AI will accelerate science. I think it will mostly accelerate disappointment.
Not because AI isn’t powerful, but because we’ve made this exact mistake before in the 1990's.
Let me tell you about it. 🧵1/
Reg Myers retweeted
Zero.
I read it three times to be sure.
For five straight years, not one young woman in England has died of cervical cancer. 🧵
Reg Myers retweeted
Presented at #ASCO26:
Among patients with previously treated metastatic pancreatic ductal adenocarcinoma, the RAS(ON) inhibitor daraxonrasib led to significantly longer overall survival and progression-free survival than chemotherapy. Full phase 3 RASolute 302 trial results: nej.md/4nWaxvM
@ASCO
ALT Graph from a study published in the New England Journal of Medicine on daraxonrasib versus chemotherapy for metastatic pancreatic cancer. The x-axis represents months, and the y-axis shows the percentage of patients alive. Two lines indicate survival rates: daraxonrasib (blue) and chemotherapy (gray). The bottom section lists patients at risk over time. Title and journal logo are included.
Reg Myers retweeted
Cheers, chills, and a standing ovation when RASolute 302 showed unprecedented survival on daraxonrasib for patients with progressive pancreatic cancer
Seldom do you sense you’re witnessing a historic moment in cancer care but this feels like ras targeting has arrived
#ASCO26
Reg Myers retweeted
New Quanta article looks at one of the coolest tiny machines in biology - the bacterial flagellar motor. It’s basically a microscopic spinning engine that bacteria use to move.
After decades of trying to fully understand it, scientists are finally figuring out how it actually works. The motor is powered by a flow of charged particles (kind of like a tiny battery), which creates force and makes it rotate.
So what looks like something alive and mysterious is really just an incredibly advanced microscopic machine running on the same basic rules as everything else.
More broadly, the article addresses the idea of a "life force." It argues that no special force is needed to explain life. Instead, biological activity arises from physical processes that operate far from equilibrium, where constant energy flow keeps the system active and organized.
The flagellar motor shows that living systems can be understood as energy driven, self organizing systems. What appears to be uniquely "alive" can be explained by standard physical laws, such as thermodynamics and molecular interactions.
Physics pushed to an extreme level of complexity.
Reg Myers retweeted
The POIESIS Trial is seeking participants aged 18+ for a large global Phase 3 study in patients with myelofibrosis who have never been treated with a JAK inhibitor.
Want to know more? Visit us today!
Reg Myers retweeted
Brandolini’s Law (also known as the bullshit asymmetry principle):
The amount of energy needed to refute bullshit is an order of magnitude bigger than that needed to produce it.
Reg Myers retweeted
🚨 The older the sperm, the more likely it is to cause autism
Sequencing sperm using nearly error-free sequencing → measure % sperm carrying disease-causing mutations:
2% at age 30 → 4.5% at 70
Most were autism genes
New paper in @Nature today 🧵
ALT https://www.nature.com/articles/s41586-025-09448-3#Fig3
Reg Myers retweeted
The problem isn’t that people don’t know.
It’s that they trust people who don’t know - as long as they sound confident.
Listen to me on this one, please: 🧵👇1/
Reg Myers retweeted
I've worked in industry for 20 years. Many studies are funded by industry.
Some people say: "Don't trust them. They're biased."
But here's the uncomfortable truth:
Without industry studies, most of the safety data you rely on wouldn't exist.
Let me explain. Want to approve a new pesticide or drug?
You need data:
→ Toxicology.
→ Residue data.
→ Carcinogenicity.
→ Environmental fate.
→ Endocrine disruption.
→ Reproductive studies.
→ Chronic exposure tests.
These studies are required by regulators. Guess who pays for them?
Industry doesn’t do these studies for fun. They do them because they’re legally mandated.
EFSA, EPA, ECHA, FDA, ANSES - all require massive data packages.
Some submissions are 100,000+ pages. They take years and cost millions.
No university is going to do that.
Industry studies don’t stay behind closed doors. They’re:
→ Audited.
→ Publicly available.
→ Reviewed by independent experts.
→ Summarized in regulatory assessments.
They’re not hiding in some secret vault. They’re sitting on EFSA’s website.
"But they’re biased!"
Yes - every study has potential for bias. That’s why the methods matter.
Industry studies follow guidelines, GLP protocols, and strict regulatory checklists.
Not blog-science. Not cherry-picked stats.
Structured.
Transparent.
Reproducible.
Academics often publish hypothesis-driven research.
Industry? They test everything:
→ What happens at low dose?
→ What happens over 2 years?
→ What if the animal is pregnant?
→ What about bees? Soil? Water?
This isn’t just science.
It’s exhaustive documentation.
EFSA doesn’t rubber-stamp anything.
Neither does the EPA.
They dissect every study line by line.
Then they ask for more.
If the study was junk - they’d reject it.
If you throw out industry studies, here's what happens:
→ No new medicines.
→ No safer chemicals.
→ No food innovations.
→ No climate-friendly fertilizers.
→ No modern toxicology databases.
You don’t get precaution.
You get paralysis.
So what should we do?
→ Push for open science.
→ Demand transparency.
→ Allow independent reanalysis.
But don’t discard industry studies just because of who funded them.
Evaluate the evidence - not the logo on the lab coat.
Industry studies are not perfect.
But without them, we’d still be guessing.
Science isn’t about who you trust.
It’s about what you can prove - under scrutiny.
And these studies face more scrutiny than most.
Understand the process.
Read the methods.
Follow the data.
Not the headlines.
Seen a story that dismissed a study just because it was industry-funded? Share it.
♻️ Repost to push back against bias in the name of science.
Reg Myers retweeted
The POIESIS Trial is seeking participants aged 18+ for a large global Phase 3 study in patients with myelofibrosis who have never been treated with a JAK inhibitor.
Want to know more? Visit us today!
Reg Myers retweeted
We are recruiting participants aged 18+ for our myelofibrosis Phase 3 clinical trial. POIESIS Trial is a large global study of patients with myelofibrosis.
Learn more about our investigational treatment, explore study locations, and see if you qualify!
Reg Myers retweeted
We are recruiting participants aged 18+ for our myelofibrosis Phase 3 clinical trial. POIESIS Trial is a large global study of patients with myelofibrosis.
Learn more about our investigational treatment, explore study locations, and see if you qualify!
Reg Myers retweeted
The POIESIS Trial is seeking participants aged 18+ for a large global Phase 3 study in patients with myelofibrosis who have never been treated with a JAK inhibitor.
Want to know more? Visit us today!
Reg Myers retweeted
We are recruiting participants aged 18+ for our myelofibrosis Phase 3 clinical trial. POIESIS Trial is a large global study of patients with myelofibrosis. Learn more about our investigational treatment, explore study locations, and see if you qualify at poiesis-trial.com/