i died at Altamont
Grover’s Corners, NH
Joined September 2013
- Tweets9.5K
- Following139
- Followers115
- Likes12.3K
I’m an Octopuses Garden truther. I think Ringo was singing about a real life place that exists and where the events of the song occurred.
really fascinating
Kratom (Mitragyna speciosa) extract has demonstrated anti-inflammatory activity, but its potential for rectal administration in hemorrhoid-associated inflammation has not been investigated. This study aimed to develop kratom extract suppositories, evaluate their physicochemical properties, and assess the effects of rectally administered kratom extract in a croton oil-induced hemorrhoid–like model in ICR mice. Kratom ethanol extract was incorporated into polyethylene glycol (PEG)- and Witepsol H15-based suppositories at a loading equivalent to 20 mg mitragynine per suppository. Hardness, disintegration, dissolution, and stability were assessed. The selected PEG-based formulation remained stable for at least 4 months under the conditions tested. For in vivo evaluation, kratom extract was suspended in PEG 400 and administered rectally once daily for 7 days after 3 days of croton oil treatment, at doses equivalent to 2.5, 5, or 10 mg of mitragynine. Tribenoside (2 mg) in the same vehicle served as the reference treatment. Treatment with tribenoside and the kratom extract at doses equivalent to 2.5, 5, and 10 mg of mitragynine significantly reduced recto-anal lesion scores compared with the vehicle–treated group. Histological assessment showed significant reductions in tissue injury, goblet-cell depletion, and mast-cell infiltration at all three kratom extract doses. The PEG 400-based formulation did not significantly affect defecation frequency, fecal water content, gut transit time, or evacuation time. These findings support further investigation of rectal kratom formulations for the local treatment of hemorrhoid-associated inflammation.
frontiersin.org/journals/pha…
no fucking way
Texas' new attorney general Nathan Johnson has revealed that he composed the score for 67 episodes of ‘DRAGON BALL Z’ as well as 5 of the Dragon Ball movies.
(Source: variety.com/2026/artisans/ne…)
David Kahnstein (anglicized, ‘Constine’) ☮️✡️🛐 retweeted
👊💚Great job to all the Michigan Kratom Consumers and Advocates that made it out to the polls and helped to flip the State blue!
Earlier this year, Republicans aggressively and with dirty, underhanded tactics pushed a blanket bill (HB 5537) through the House that would have banned all forms of kratom and worse yet, criminalize kratom consumers.
All 47 House Democrats who voted on HB 5537 opposed it.
Last Night Democrats won the House and retained the Senate.
Furthermore, the executive director of endkratomaddiction is from Michigan. According to other Michigan advocates, that prohibition organization was putting in hard work to make the State Red.
Yet Kratom Consumers took a stand and helped to turn the State blue.
Yet another State that weaponized their vote and said Hell NO to drug prohibition. This was a big Victory for Michigan!!
The war against medicinal/recreational plants in this nation whether Marijuana or Kratom need to END.
#KeepKratomLegal #KratomSavesLives #KratomBan
David Kahnstein (anglicized, ‘Constine’) ☮️✡️🛐 retweeted
In lieu of recent events on the Timeline these past few days
David Kahnstein (anglicized, ‘Constine’) ☮️✡️🛐 retweeted
White House Bunny Rabbit Has Nothing to Say About Midterms, Plenty to Eat tmz.me/4AwALKz
all the kids in the pool closing their eyes and playing the poolside call-and-response game called “Obamna Soda”
