Transitional year intern @mhshospital, future radiology resident @UCSF. Penn MSTP alumđ©șđ§Ź, Gates-Cambridge Scholar, UF gradđ. I want to believeđœ.
Coral Springs, FL
Joined June 2010
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Proud to announce Iâll be going to Memorial Healthcare in South Florida for 1 year of general medicine, then University of California - San Francisco for 4 years of Diagnostic Radiology!!
Eternally grateful to my parents and family for their support since day 1. @RadsUcsf
Juan C Serrano, MD, PhD retweeted
Now online! APOBEC3A and APOBEC3B drive distinct mutational landscapes in tumors. We showed how A3A and A3B substrate preferences for different hairpin structures can be exploited to identify patients' tumors with mutations caused by either A3A or A3B. nature.com/articles/s41467-0âŠ
Had a great time at my first #RSNA hearing about cutting-edge radiology research and meeting colleagues as a #FutureRadRes. Wonderful to see MCCormick Place from SkyEdge as well!
@RSNA @RSNATrainees â at Chicago, IL
Thought Spanish-speaking #MedTwitter would get a kick out of this exchange with my dad.
#Match2024 #RadTwitter #FutureRadRes
Juan C Serrano, MD, PhD retweeted
Although the implosion of OceanGateâs Titan was heard from the very beginning and death was certain, resources were still used to rescue those on board. When itâs migrants who may very well survive, resources suddenly become scarce. The wretched of the earth are not worth saving.
Juan C Serrano, MD, PhD retweeted
Excited to share our paper out today in @nchembio! DM-Seq is our non-destructive approach for detecting DNA methylation. We even benchmarked against the recently acquired diagnostic technology TAPS (by Exact, maker of Cologuard). Thread! đ§”nature.com/articles/s41589-0âŠ
Juan C Serrano, MD, PhD retweeted
My name is Muhil, and I first came to the United States when I was 2 years old. Despite living here lawfully for two decades, I did not receive my green card with my family because I aged out.
When the fellow starts ranting about med students not really learning and relying on those âsketchy cartoonsâ
Juan C Serrano, MD, PhD retweeted
(with phd friends) ugh clinicians am I right
(with md friends) ugh researchers am I right
(with md phd friends) my unhappiness is a product of the choices I have made
Juan C Serrano, MD, PhD retweeted
24 days ago I learned my daughter was dying in utero, and if untreated I risked preeclampsia and stroke. Termination is illegal in NC after 21 weeks, which I was, even when she had no hope of surviving and I was in danger. Because I had the means to leave, Iâm ok and recovering.
Juan C Serrano, MD, PhD retweeted
1/ Excited (and relieved) to share our new work with @arjunrajlab on identifying intrinsic factors marking rare somatic cells âprimedâ to become pluripotent stem cells before reprogramming even starts @CAMBUpenn, @PennGenetics, @PennEpiInst, @pennbioeng.
biorxiv.org/content/10.1101/âŠ
Extremely excited to be able to share this with the wider #deaminase community.
This manuscript started from a simple question: to create inhibitors of DNA deaminases, could we go beyond mimicking the individual bases to mimicking the very structure of the DNA backbone?
Hot off the press! By leveraging insights into a deaminase's preferred substrate secondary structure, we developed a specific & potent nanomolar inhibitor of APOBEC3A, a genomic mutator implicated in #cancer development.
pubs.acs.org/doi/10.1021/acsâŠ
These efforts could not have been possible without the strong collaboration with the @DmochowskiUPenn lab and Dora von Trentini, as well as the amazing @Berrios_KN and @AleksiaBarka.
I could not have picked a more supportive lab than the @KohliLab to pursue the PhD portion of my MD-PhD and develop my skills as a chemical biologist. Our DNA dumbbell story is yet to be over, so be on the lookout as we advance our modulators to the cellular realm!