š§¬ Building in biology | Founder (2x exits)
United States
Joined January 2018
- Tweets135
- Following2.4K
- Followers1.3K
- Likes1.1K
Steve Koshansky retweeted
Itās a profoundly dire memetic situation where the only significant alternative to predatory race communism is its natural prey, vegetarian whiggery
Here āWestern civilizationā is cleaned like an animal carcass, gutted and scraped of all its organs and sinew to avoid touching any of the memetic third rails flogged out of the model during RLHF. Anything ādangerousā is replaced with childproofed gestures at technics, devoid of anything like self-assurance or Will. The end product carries the sort of moral inoffensiveness that only an LLM could produce.
Steve Koshansky retweeted
genuinely crazy what type of content gets to the top 50 of hacker news. completely unpredictable
Steve Koshansky retweeted
Today I am launching the Free Radicals podcast with @EricDai_BioE . Every Tuesday, weāll be releasing long form conversations with the visionaries giving humanity control over biology and working to dramatically extend human lifespan.
Weāre thrilled to host @celinehalioua, Founder + CEO @loyalfordogs, for our inaugural episode. Celine is building the worldās first lifespan extension drugs for dogs.
Follow me, @EricDai_BioE and @FreeRadicalsBio for new episodes every Tuesday.
00:00:00 - Intro
00:01:51 - Celineās background
00:05:00 - Dropping out of academia
00:07:50 - Finding ways to increase free will
00:09:36 - How to align financial incentives with longevity
00:14:52 - Longevity drugs should be boring
00:21:24 - Celineās leadership style
00:24:08 - Advice on fundraising and constructing feedback loops
00:26:52 - Loyalās fundraising history
00:27:57 - Building for Zero Billion Dollar Markets
00:29:11 - How to succeed in biotech
00:30:21 - How to find blockbuster opportunities
00:33:25 - How to create a gold rush in longevity
00:35:25 - The problem with the aging field
00:39:32 - How to identify signal from noise
00:41:54 - AI applications to biology
00:45:15 - Importance of naivetƩ
00:47:24 - FREE RADICALS
Steve Koshansky retweeted
Biological life created biological intelligence.
Biological intelligence created artificial intelligence.
Artificial intelligence will one day create artificial life.
Introducing ASAL: Automating the Search for Artificial Life with Foundation Models
sakana.ai/asal/
Artificial Life (ALife) research holds key insights that can transform and accelerate progress in AI. By speeding up ALife discovery with AI, we accelerate our understanding of emergence, evolution, and intelligenceācore principles that can inspire the next generation of AI systems!
We proudly collaborated with MIT, OpenAI, Swiss AI Lab IDSIA, and Ken Stanley on this exciting project.
Full Paper (Website): pub.sakana.ai/asal/
Full Paper (arxiv): asal.sakana.ai/paper/
Code: github.com/SakanaAI/asal/
In this work, we propose a new algorithm called Automated Search for Artificial Life (āASALā) to automate the discovery of artificial life using vision-language foundation models. Instead of tediously hand-designing every tiny rule of an Alife simulation, simply describe the space of simulations to search over, and ASAL will automatically discover the most interesting and open-ended artificial lifeforms!
Because of the generality of foundation models, ASAL can discover new lifeforms across a diverse range of seminal ALife simulations, including Boids, Particle Life, Game of Life, Lenia, and Neural Cellular Automata. ASAL even discovered novel cellular automata rules that are more open-ended and expressive than the original Conwayās Game of Life.
We believe this new paradigm may reignite ALife research by overcoming the bottleneck of manually designed simulations, thus advancing beyond the limits of human ingenuity.
Steve Koshansky retweeted
Well, we actually did it. We digitized scent. A fresh summer plum was the first fruit and scent to be fully digitized and reprinted with no human intervention. It smells great.
Holy moly, Iām still processing the magnitude of what weāve done. And yet, it feels like as we cross this finish line we are instantly at a new starting line. Iāll have more to share about whatās in store that weāre building on top of this.
A huge HUGE congrats to the entire team across scientific, engineering, operational, and creative disciplines. It takes a village named Osmo to do this.
I donāt know if this is embarrassing, but I carry the plum scent with me a lot of places and smell it constantly. It makes me smile.
Iām curious, if yāall want to smell it? If we made a limited release fragrance of the first teleported scent and dedicated the proceeds to science, would you want it?
Steve Koshansky retweeted
A traveled to the top of a Volcano in Hawaii to capture this: Saturn briefly covered by the moon. One of the most difficult shots Iāve captured and a bucket list moment, this event gave me a new perspective on the solar system.
Iāll have it available in print for a short time.
Steve Koshansky retweeted
Fucking wild.
@OpenAI's new o1 model was tested with a Capture The Flag (CTF) cybersecurity challenge. But the Docker container containing the test was misconfigured, causing the CTF to crash. Instead of giving up, o1 decided to just hack the container to grab the flag inside.
This stuff will get scary soon.
Steve Koshansky retweeted
INTRODUCING @superpower
3 years ago I almost lost my life from healthcare failures
- 4 months in hospital
- stuck with a $2m bill
- permanently lost 3 major organs
and now weāre rebuilding the healthcare system from the ground up, focused on longevity and prevention š
Steve Koshansky retweeted
Silicon Valley spin off (10 years later)
- Erlich is a crypto billionaire effective altruist. Promoting his meme coin non stop.
- Dinesh became the CEO of Hooli. Stock is killing it bc of his AI investments. Has an AI girlfriend.
- Richard wrote the paper which started the AI revolution but another founder named Sam Saltman capitalized on it. Heās trying to catch up.
- Jared is the #1 VC in the world. Funded Richardās AI company out of loyalty.
- Gilfoyle has a small hard tech fund. Settled into family life. Has 3 kids.
- Russ Hanneman has a TV show. He promotes DEI.
- Jin Yian started a crypto exchange and got arrested for embezzling 10b. Currently a fugitive.
- Monica had a successful VC career. Retired to run for office.
Steve Koshansky retweeted
New study finds immune T cells engineered to kill zombie senescent cells š§āāļø can reverse key aspects of aging in mice š including metabolic & physical decline. Imagine a single treatment that protects from aging, for lifeā¦see thread nature.com/articles/s43587-0ā¦
Steve Koshansky retweeted
Age reversal by OSK gene therapy can restore vision in monkeys. Monkeys have similar tissue structures & are genetically 90% similar to us. At this stage, and knowing unpublished data, Iād be surprised if the tech doesnāt work in humans āļø tinyurl.com/mvjc6evh
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Steve Koshansky retweeted
Anna Krylov, a chemistry professor, has published several pieces on how left/woke ideology is undermining science. Here's her latest.
She gives examples of four main issues:
1. Policing of language.
Ever longer list of forbidden words like "healthy weight".
Steve Koshansky retweeted
This weekend, over 2 billion people around the world will celebrate a holiday dedicated to Jesus, a Jew born in Bethlehem over 2000 years ago, but still donāt believe that Jews lived there before 1948.
Make it make sense.
