Postdoc @BostonChildrens & @HarvardMed, PhD @uOttawa|Uncovering the mysteries of immunity & inflammation🧪🧬
Boston, MA
Joined October 2021
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- Following73
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Stephanie Hajjar retweeted
Curious about microenvironment #pH in tissue #homeostasis and #inflammation? We discuss pH sensing®ulation in the framework of homeostatic&inflammatory circuits and why immune cells may be key. Kudos to @stephajjar @harvardmed @BostonChildrens @TrendsImmuno @CellPressNews
pH sensing at the intersection of tissue homeostasis and inflammation #immunology dlvr.it/Sw3wdG
Stephanie Hajjar retweeted
3 amazing papers just out @Nature, the kind worth giving up sleep for🦉
Spatial multi-omics human maps:
-placenta: MIBI & DSP
-intestine: CODEX & snRNAseq & snATACseq
-kidney: Visium & scRNA & scATAC
After sequencing single cells, we are now finally putting them back together🧵
Stephanie Hajjar retweeted
Excited to share our latest article published in @plospathogens: journals.plos.org/plospathog… #plospathogensauthor
Stephanie Hajjar retweeted
Our new manuscript by Hoang et al. Thanks to all who contributed especially our 5’leader Dr. Hoang!
New #JITC article: Adaptation of transgene mRNA translation boosts the anticancer efficacy of oncolytic HSV1 bit.ly/3lvjtwt @samworkenhe @TommyAlain3
Stephanie Hajjar retweeted
Today is International Day of Women and Girls In Science! To celebrate #WomenInScienceDay, we asked a few of our Broadies about the impact #WomenInScience make.
Stephanie Hajjar retweeted
IL-23 signaling is required for baseline and IL-23-inducible IFN-γ immunity in both Vδ2+ γδT and MAIT cells @PhilippotQ @anne_puel @casanova_lab
Jacinta Bustamante @SciImmunology
science.org/doi/10.1126/scii…
Stephanie Hajjar retweeted
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📢And here it is: 😍
We are excited to announce the first international workshop on “Metabolism in the single cell era”.
It will be held in Bordeaux, France from the 20th to 22nd of September 2023
ALT Some of the titles might need editing
Stephanie Hajjar retweeted
Discovery of bone lymphatics & their role in blood & bone regeneration @CellCellPress
👇
cell.com/cell/fulltext/S0092…
Very grateful to: fantastic - editor & reviewers,
funders @The_MRC @ERC_Research
& support from @MRC_HIU @MRC_WIMM @RoyalMicroSoc @Official_BSCB
Stephanie Hajjar retweeted
Amazing to see our Bone Marrow Organoid paper out today in the Feb issue of @CD_AACR
@AbAttacks @beth_psaila
Even more exciting to see an amazing Spotlight article written about it! Thank you @marta_derecka and John Crispino 🤩 - I love it!
tinyurl.com/39xa82uk
First bone marrow organoids - paper and commentary in print today in Cancer Discovery.
Paper - bit.ly/3X4clDP
@CD_AACR @AbAttacks @unibirm_TRT @ICVS_UoB @unibirm_MDS
#bonemarrow #organoid
Stephanie Hajjar retweeted
One of the most impressive T cell papers in the past decades. A truly humbling experiment and incredibly important insights into T cell biology. @Masopust_Vezys truly amazing. A must read for all T cell biologist (all immunologists really). #instantclassic nature.com/articles/s41586-0…
Stephanie Hajjar retweeted
Identification of hematopoietic stem cells residing in the meninges of adult mice at steady state cell.com/cell-reports/fullte… – at St Louis, MO
Stephanie Hajjar retweeted
Dysregulation of temporal metabolic adaptability is a key 🔑 feature of #immunosuppression.
Drs. Huiyang Yu, Nicolas Jacquelot, and Gabrielle Belz review how #metabolism regulates lymphocytes beyond the classical T cell subsets.
📂 bit.ly/3DkXm0G
Stephanie Hajjar retweeted
Secreted immune metabolites that mediate immune cell communication and function dlvr.it/ScJ4bd #immunology
Stephanie Hajjar retweeted
During re-infection, primed CD103+ gut TRM cells turn on but don’t expand and CD103- gut TRM cells seed and renew CD103+ TRM cell populations in gut tissue, finds a new study in mice. @TU_Muenchen
📄: scim.ag/qE
Stephanie Hajjar retweeted
#LiveForever! Nakanishi &co show @Nature that senescent cells are inflammatory & present an interferon signature, but are protected from T cell killing by up regulating PDL1, thus favoring inflammaging! Anti-PD1 decreases senescent cells in aged mice! doi.org/10.1038/s41586-022-0…
Stephanie Hajjar retweeted
The difference between doing a project and presenting it. An observation can lead to many avenues of explorations before focus turns to a specific discovery. Presenting it, in a talk / paper, follows inversely, with broad perspectives coming before & after the specific discovery.
Stephanie Hajjar retweeted
Fascinating: lactate sensor shows that mitochondrial lactate pools are ~5x bigger than nucleo-cytosolic pools cell.com/cell-metabolism/ful…; are there implications for our reliance on whole cell pyr/lac as readout of cytosolic NAD/NADH?
Stephanie Hajjar retweeted
Meta just dropped 600+ million protein structure predictions, made using a large language model.
My latest for @Nature
nature.com/articles/d41586-0…
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