VirHostNet 2.0

🧬Evo, the first foundation model trained at scale on DNA, is a Rosetta Stone for biology. DNA, RNA, and proteins are the fundamental molecules of life—and cracking the code of their complex language is an ongoing grand challenge. 🔬Today in @ScienceMagazine, the labs of Arc Innovation Investigator @BrianHie and Arc Co-Founder @pdhsu explain how Evo captures two fundamental aspects of biology: the multi-modality of the central dogma and the multi-scale nature of evolution. Evo excels at prediction and generation tasks across all of these molecules and their interactions. An exciting example of what Evo can do: the team used it to design a totally new CRISPR system, including a guide RNA that makes Cas9 cut even better. Evo can also design DNA sequences over one million base pairs in length, reaching the size of many real genomes. 🧠Check out the paper now in Science: science.org/doi/10.1126/scie…