Genomic Vision retweeted
Really pleased to have been part of this study by the Bielinsky lab @AKBiela studying the functional consequences of patient associated mutations in MCM10
nature.com/articles/s41467-0…
Genomic Vision retweeted
A new study from @HironoriFunabi1 with @Simona_Giunta shows that centromeres possess a special mechanism to facilitate their replication and suppress cancer-causing chromosome translocations.
pnas.org/content/118/10/e201…
Genomic Vision retweeted
Thanks @institut_curie for the nice article institut-curie.org/actualite… on our recent paper published in PNAS pnas.org/content/118/10/e201… and on my overall research program
Genomic Vision retweeted
First paper of 2021 from the lab! A 4 years full collaboration with @HironoriFunabi1 @Simona_Giunta . What an amazing journey! Thanks to all authors for the contributions, specially to @sol_herve. Great to see it out at pnas.org/content/118/10/e201…
Genomic Vision retweeted
So happy to make this our first official @GiuntaLab tweet and share the fruit of a wonderful collaboration with @FachinettiLab @HironoriFunabi1 @sol_herve now published! with many thanks also to @MaintainGenome @LordDNA et al. @Simona_Giunta #brandnewlab
pnas.org/content/118/10/e201…
Genomic Vision retweeted
CENP-A chromatin prevents replication stress at centromeres to avoid structural aneuploidy dlvr.it/RtvS92
Genomic Vision retweeted
Des chercheurs de l’Institut Curie ont mis en lumière le rôle de la protéine CENP-A dans la réplication de l’ADN centromérique afin d’empêcher l’apparition d’anomalies chromosomiques structurelles. 🧬
curie.fr/actualite/publicati…
Genomic Vision retweeted
SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors. dlvr.it/Rs4DdG
Genomic Vision retweeted
SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors. dlvr.it/Rs4HMC
Genomic Vision retweeted
Thank you to all who participated in the BIO-Europe Spring® Digital ticket giveaway! Congrats to Imen Mestiri from @GenomicVision_ - you are the lucky winner of the free ticket! 🎉 Don't forget to register to the event if you haven't yet 👉🏻loom.ly/Da66_Rc 👈🏻 @EBDgroup
Genomic Vision retweeted
Clinical and Translational Report in this issue of CellStemCell: MYC Promotes Bone Marrow Stem Cell Dysfunction in Fanconi Anemia cell.com/cell-stem-cell/full…
Genomic Vision retweeted
Neat proteomic analysis + cell expts by @DrAndyBlackford's group showing which Bloom syndrome complex components interact with ssDNA binding protein RPA. RPA-binding promotes recruitment of BLM to ssDNA damage sites e.g., stalled replication forks. nature.com/articles/s41467-0…
Genomic Vision retweeted
Great work from our own Fiona Simpkins!
In this @NatureComms , @Penn_OCRC team investigates the effect of a new combination of inhibitors in ovarian cancer models. Fork asymmetry has been assessed by #molecularcombing in platinum-resistant cell lines, treated with PARPi, ATRi or a combination.
rdcu.be/ccbGg
Genomic Vision retweeted
Ruggiano and @Kramadan2 discuss the roles of DNA-protein crosslink (DPC) proteases, which digest the protein component of crosslinks, in DPC repair and beyond. nature.com/articles/s42003-0…
Genomic Vision retweeted
I am delighted to be speaking at the PARP & DDR Inhibitors Digital Summit taking place in just 3 weeks, from January 26 – 28. If you would like to hear from me and other expert speakers, you can register your place here: ter.li/midsq2
Genomic Vision retweeted
Online Now: CARM1 regulates replication fork speed and stress response by stimulating PARP1 dlvr.it/Rq1xbh
Genomic Vision retweeted
We are immensely pleased to continue our long-term association with Genomic Vision. We are completely assure of Genomic Vision management's conviction to achieve the set objectives and with Winance financing arrangement in place, and
Genomic Vision retweeted
We are very pleased to share our latest published work from the lab. Phenomenal effort by @elaine_sanij and the entire team!
nature.com/articles/s41467-0…
@PearsonRick @PeterMacRes
Genomic Vision retweeted
Very pleased to see this great work by so many wonderful collaborators finally published! #CancerResearch
nature.com/articles/s41467-0…
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Genomic Vision retweeted
So proud of this work and our team @PearsonLab1 We are excited that this new treatment approach shows promising potential in some ovarian cancers that currently have very limited treatment options @PeterMacRes @WEHI_research @JCSMR @SVIResearch @QIMRBerghofer
An inhibitor of RNA polymerase I overcomes resistance to PARP inhibitors in PDX models of high grade serous ovarian cancer.
go.nature.com/36BBP2O
#CancerResearch
@elaine_sanij @PearsonRick @PeterMacCC @PeterMacRes























