ALT Graphic from the Addison’s Disease Self-Help Group (ADSHG) with the headline “Campaigning for Safer Adrenal Crisis Care” in bold red text. Above this is a red button labelled “Patient Safety Risk.” Supporting text explains that an adrenal crisis is a life-threatening medical emergency requiring a time-critical injection of hydrocortisone. A large grey panel contains a red warning heading: “Other life-threatening conditions have auto-injectors or pre-filled syringes. Adrenal crisis doesn’t.” Additional text explains that the hydrocortisone injection process is complex and involves multiple steps, leaving patients struggling to self-inject life-saving treatment. It also states that patients’ lives are at risk and hospital admissions are increased because of delayed treatment. Below the text is a red circular illustration showing a syringe, vial and ampoule, with warning symbols. The purple footer contains the call to action “Help us campaign for change” followed by a white arrow.

ALT Graphic from the Addison’s Disease Self-Help Group (ADSHG) with the heading “Current hydrocortisone injection process” in bold white text on a red background. At the top right is a white button labelled “Campaigning for Safer Adrenal Crisis Care.” The graphic describes four challenges with the current hydrocortisone injection process, with a white icon accompanying each section. “Complex & Lengthy” explains that preparation involves 12+ steps, requiring good vision, a steady hand, focus and manual dexterity. “Challenging” states that self-injection is extremely difficult (or impossible) during a life-threatening adrenal crisis, when experiencing pain, vomiting, diarrhoea, brain fog, dizziness and loss of consciousness. “Low Success Rate” states that, in a recent UK study, only 18% of patients were able to self-inject. “Increased Hospital Admissions” states that, in the same study, admission to hospital was 34% higher when the injection was delayed and given by a paramedic or in A

ALT Graphic from the Addison’s Disease Self-Help Group (ADSHG) with the heading “An improved injection process will…” in bold white text on a teal background. At the top right is a white button labelled “Campaigning for Safer Adrenal Crisis Care.” The graphic describes four improvements to the hydrocortisone injection process, with a white icon accompanying each section. “Be Simplified” explains that the process will require fewer preparation steps and will be easier to use for people with poor sight or hand movements. “Be Designed for Ease” describes treatment that is pre-measured and ready to inject, with Act-O-Vial® identified as the short-term option and a pre-filled syringe or auto-injector as the long-term option. “Be More Successful” highlights an increased chance of timely self-injection to treat adrenal crisis. “Give Better Health Outcomes” states that timely treatment will reduce the risk of hospital admissions. A large circular icon on the left shows a pre-filled injectio