Neurosurgeon-Scientist-Runner-Father

San Francisco, CA
Joined September 2017
Excited to publish the latest story in my lab's long-standing collaboration with @kumarlabucb in which we continue our efforts to use bioengineered hydrogels and large-scale screens to identify novel druggable mediators of the invasion that is a defining hallmark of glioblastoma.
Envisioning therapeutic agents that target invasion in aggressive brain cancer: doi.org/10.1172/jci.insight.… Here, Sanjay Kumar @kumarlabucb @UCBerkeley, Manish K. Aghi @ManishKAghi & team @UCSFCancer applied a druggable genome screen to #Glioblastoma cells invading brain-mimetic hydrogels, revealing Aurora B and LMW-PTP as invasion mediators. Time-lapse video of 3D hydrogel invasion shown at 10x original playback @the_asci
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Manish Aghi, MD PhD retweeted
.@ManishKAghi shares his tips for fellows looking to launch a research lab and establish a successful faculty career as a neurosurgeon-scientist, emphasizing the importance of mentorship during the early-career stages. #AANS2026
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Manish Aghi, MD PhD retweeted
Today’s the last day of #AANS2026, but our team is still going strong, covering everything from the latest in brain tumor surgery to debates in neurotrauma and practical career advice for transitioning to a faculty position. @ManishKAghi @jakeyoung11 @DrDiGiorgio
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Manish Aghi, MD PhD retweeted
Four million physician hours are spent on mandatory modules each year. They represent not just clinical time lost but “evenings reclaimed and cognitive load reduced.” Redundant training and low-value modules should be a thing of the past. jamanetwork.com/journals/jam…
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Great to host our good friend and former @NeurosurgUCSF colleague @DeanChouMD currently leading the spine program @ColumbiaNeuro for the annual Charlie Wilson lectureship. Dean is a spectacular teacher, scholar, and surgeon and we enjoyed having him back at UCSF
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Good times at the #SNO2026 Friday poster session with Venina Kalistratova, @meeki_lad, and @Ankita_Sati_ representing Aghi lab in lovely Honolulu !
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Manish Aghi, MD PhD retweeted
We're looking forward to reconnecting with our colleagues next week at #SNO2025! Check out the full list of presentations from our team of researchers: braintumorcenter.ucsf.edu/ne… @LabRaleigh @ManishKAghi @jakeyoung11 @josephcostell14 @VasuLabUCSF @Dr_PViswanath @bnamdphd @NeuroOnc
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Manish Aghi, MD PhD retweeted
We’re excited to be in L.A. for #2025CNS! Check out all the incredible work that our faculty, residents, and medical students are doing: neurosurgery.ucsf.edu/news/u… @ManishKAghi @JohnKYueMD @jakeyoung11 @DorisWangLab @SavastanoLuisMD @EWinklerMDPhD @UCSFHospitals
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Glad to announce that I’ll soon be joining Mayo Clinic Florida as their new Chair of the Department of Laboratory Medicine and Pathology. Grateful to @NU_Pathology, @BrainTumorInst, @NUFeinbergMed, and @NeurosurgeryNM for a great experience, will miss you!
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Great being a part of this session with such wonderful neurosurgical colleagues at the @PituitarySoc meeting in San Francisco today
Had a fun time lecturing at the @PituitarySoc Congress meeting in San Francisco today in a dedicated session for the International Society of Pituitary Surgeons (#ISPS) along with these esteemed neurosurgeon colleagues! @ManishKAghi @drjfm_stanford @DanielYoshor Nelson Oyesiku #Neurosurgery #Endocrinology #Pituitary @TheEndoSociety @uscbtc @NeurosurgeryUSC
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Great to see old friends and present work from my lab on our novel immunomodulatory gene therapy approach at #ICBTRT2025, one of my favorite brain tumor meetings. Hokkaido was a lovely venue and it was wonderful having family with me and meeting families of so many colleagues
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Congrats to @robcosorio on the well-deserved award and @AANSNeuro plenary for his single-cell analysis of pituitary tumors done with his co-resident @josephoh0517. And thanks to Columbia Softball for supporting this award and other educational initiatives in neurosurgery.
Honored and grateful for the award and the opportunity to present our work at @AANSNeuro ! Huge thanks to @ManishKAghi and everyone at @NeurosurgUCSF for their support.
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Congrats to @UCSFMedicine MS3 @PoojanShuk90434 for winning the Southeastern Brain Tumor Foundation Award for his study in my lab developing a single cell atlas of patient GBMs progressing on bevacizumab - we need to better understands mechanisms of adaptive resistance in GBM
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Great job by @UCSFMedicine first year student Cameron Ehsan winning best poster @AANSNeuro meeting for his work looking at factor associated with match success. #AANS2025
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Great job by UC Davis third year med student Venina Kalistratova presenting her work on adaptations to oxidative stress in brain metastases that promote invasion at the @AANSNeuro rapid fire tumor session #aans2025
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Congrats to my former lab member and current @NeurosurgUTH resident @chandraankush for his @AANSNeuro plenary talk defining tGLI1 as a mediator of resistance to CDK4/6 inhibitors and chemoradiation in GBM. #AANS2025
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Congrats to @NeurosurgUCSF PGY1 @robcosorio for his @aans plenary talk describing work completed by him and his coresident @josephoh0517 in my lab defining PitNET tumors st the single cell level, challenging the current classification scheme. #AANS2025
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Thank you very much to @NSTumorSection and the panelists @hadjiMDPhD @chandraankush @AshishHShah4 for inviting me to speak on this important topic!
Powerful session with @ManishKAghi (@NeurosurgUCSF) on managing recurrent glioblastoma—honored to hear from a leader in the field. @NSTumorSection @hadjiMDPhD @chandraankush @AshishHShah4
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Congrats and best of luck !
I am beyond thrilled to begin my #NeurosurgeryResidency at @PennNSG & join this amazing department and resident cohort. Thank you to my mentors who made this possible, @BryanDChoi @BobCarterMD @BrianNahed. Excited to learn from @DanielYoshor & all of Penn's world-class faculty!
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