Muniesh Muthaiyan Shanmugam retweeted
Unfolded protein response (UPR), by surveillance of protein misfolding, initiating refolding or degradation & inflammation, is involved in aging. As MG is major physiological UPR activator (sciencedirect.com/science/ar…), @glo1inducer supports healthy aging. @LongevityTech @altos_labs
Muniesh Muthaiyan Shanmugam retweeted
As we mourn loss of and celebrate life of Judy Campisi, enjoy listening to interview she did for our podcast. It’s great tutorial on #cellularsenescence and her comment on “failed experiments” is classic Judy. Details about memorial service are pending buckinstitute.org/podcasts/u…
Muniesh Muthaiyan Shanmugam retweeted
I'm deeply saddened to share that we have lost a remarkable friend, a wonderful mentor and esteemed colleague, Judith Campisi. Judith's impact on those around her was profound and lasting. Her legacy will continue to inspire us all. Rest in peace, Judy. You will be greatly missed
Muniesh Muthaiyan Shanmugam retweeted
Pleased to share my newest publication about OXR1, a gene that protects the aging brain, published today in @NatureComms! A thread describing the results below 👇, and here is a link to the article: nature.com/articles/s41467-0…
@KapahiLab #Drosophila #aging #longevity #retromer
Muniesh Muthaiyan Shanmugam retweeted
What regulates the transport of autophagosomes along the axon? In @JCellBiol, @sydneycason & @ErikaHolzbaur show that mature axonal autophagosomes are transported by the #microtubule motor #dynein, activated by JIP3/4 & regulated by ARF6 & RAB10 bit.ly/3MrP5Nw
#autophagy
Muniesh Muthaiyan Shanmugam retweeted
Reproducibility trial: 246 biologists get different results from same data sets nature.com/articles/d41586-0…
Muniesh Muthaiyan Shanmugam retweeted
The 2023 NIA Summer Training @AM_OMRF was a life-changing experience! So glad to learn about grants and meet so many brilliant young scientists like @KevinMurachPhD @CoCo_Headley (my @InterSciFellows brother) @VicenziSilvia @KentLangston @mkim327 @XuZhang_Mayo @AminaAbdulAziz8!!!
Our tiny lab worms reveal big insights! My new @eLife study shows Advanced Glycation End-products (AGEs) in processed foods caused worms to overeat.
Check out! doi.org/10.7554/eLife.82446
@KapahiLab @BuckInstitute @ellie_elegans @theElegantWorm @AM_OMRF @americanaging @ScienceNews
Muniesh Muthaiyan Shanmugam retweeted
Today we are gearing up for an unforgettable Linda Partridge Farewell Symposium with a star-studded line-up of speakers - to celebrate her legacy and say goodbye. Let's make this a symposium to remember! 🥂 #LindaPartridgeFarewell
Muniesh Muthaiyan Shanmugam retweeted
It’s almost a rap for the 30th Annual Summer Training Course in Experimental Aging Research. What a great week!
Muniesh Muthaiyan Shanmugam retweeted
Sudipta does such an awesome job using the fly as an AD model. Love working with this guy! – at San Francisco, CA
@KapahiLab postdoc Sudipta Bar presenting his work on the metabolic mechanisms of #Alzheimer's disease at #BAAM! @BuckInstitute @UCSF
Muniesh Muthaiyan Shanmugam retweeted
Please read my first author research work published in “Traffic”. pubmed.ncbi.nlm.nih.gov/3526…
Muniesh Muthaiyan Shanmugam retweeted
Here is my first author method paper published in Methods Mol Biol
(Springer Nature) pubmed.ncbi.nlm.nih.gov/3541…
Muniesh Muthaiyan Shanmugam retweeted
My first author research work has been cover featured in @TrafficJournal
Muniesh Muthaiyan Shanmugam retweeted
We love glycated foods- toast, barbecue, caramel… seems like our worms like it too! And it’s produced endogenously! biorxiv.org/content/10.1101/…
Muniesh Muthaiyan Shanmugam retweeted
Be careful of eating barbecued food. A simple way to reduce glycation is to cut down sugar, steam food and avoid dry heat. Excited to share the preprint of our article on how a specific endogenous AGE drives feeding behavior and neurodegeneration. biorxiv.org/cgi/content/shor…
Muniesh Muthaiyan Shanmugam retweeted
Excited to share a preprint of our latest work on how glycation lowering compounds can reduce calorie intake increase insulin sensitivity and extend lifespan even when given late in life. 1/2 protect-us.mimecast.com/s/Pd…
Muniesh Muthaiyan Shanmugam retweeted
Have you flossed today? Link between gum disease and #Alzheimers just got stronger. Researchers @TuftsDental say F. nucleatum, which causes gum disease results in abnormal proliferation of microglial cells in the brain which creates increased inflammation. eurekalert.org/news-releases…
BBQ and Baked Food: A delicious Suffering - Won poster prize @Bay Area Aging Meeting 2022
#Advanced Glycation End products (AGEs)
#C. elegans
@KapahiLab @BuckInstitute
