@OttTorben

Neuroscientist - (Un)certainty, Cells, Dopamine&5HT - Experiments 🔗 Theory. PI Decision Circuits Lab at @bccn_berlin @HumboldtUni.

 Berlin, Germany
torbenottlab.org
Joined January 2018
  • Tweets488
  • Following428
  • Followers540
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1/ Thrilled to share the first work from the Ott lab (@OttTorben), with OpenScope at @AllenInstitute! We focused on how #psilocybin 🍄changes visual processing during active behavior in mice. We combined visual change detection with large-scale Neuropixels recordings in mice.
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Thrilled that our proposal (@OttTorben, @LabSchmitz) to investigate the effect of #Psilocybin 🍄 on cortical networks 🧠 was selected by the Openscope platform @AllenInstitute @LecoqJerome. Read more about it here: alleninstitute.org/news/mapp… #psychedelics

Mapping the brain's visual world on psychedelics, texture and time

How do neurons react to magic mushrooms? What happens in the brain when we see motion, or when we recognize grain patterns in a piece of wood?

alleninstitute.org
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Anqi Zhang@anqi_z3 Mar 2024
Come for the cool-amazing-unique brains and behaviors, stay for the general mechanisms and inspiration for artificial agents. Feat. @cris_niell @LabVallentin @kelseytyss @evolvingORs @e_mackevicius @jzavatoneveth @OttTorben Lorenz Fenk and Barbara Webb
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Attentional mechanisms enable selective processing of information. With Ruobing Xia, @Xiaomo_CCLab, and Tirin Moore, we review work across species, forms of attention, and analysis levels, revealing convergence and differences. Out today in @TrendsCognSci: sciencedirect.com/science/ar…
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nature
@Nature22 Feb 2024
Nature research paper: Synaptic wiring motifs in posterior parietal cortex support decision-making go.nature.com/42UCYj9

Synaptic wiring motifs in posterior parietal cortex support decision-making

Nature - Excitatory pyramidal neurons preferentially target inhibitory interneurons with the same selectivity and, in turn, inhibitory interneurons preferentially target pyramidal neurons with...

nature.com
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Dabei in Folge 3 der @Tagesspiegel-Reihe zu den 100 wichtigsten Köpfen der Berliner Wissenschaft: Torben Ott @OttTorben, Neurowissenschaftler am Institut für Biologie der HU & am @bccn_berlin, der zur Bewertung von Zeit aus neuronaler Perspektive forscht! tagesspiegel.de/wissen/sie-e…
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What do you get when you combine RL and predictive coding? The in vivo activity patterns of serotonin neurons. Excited to share a new theory and analysis to back it up! doi.org/10.1101/2023.09.19.5… With @NeuroNaud and @JCBeique in collab with @grossmancooper & @JeremiahYCohen. 🧵
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1/6 We are thrilled to share our latest paper published on @CurrentBiology today! @ChenYuNan347 with the support of @johanna_kostka and @SebBitzenhofer revealed that olfaction early in life is necessary for cognitive development. sciencedirect.com/science/ar…
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Mice reaching up for rewards! 🐭💪🏻 Current tasks for assessing motivation may have some extra cognitive demands not purely related to physical effort which may confound result interpretation and outcomes. We´ve developed a task to minimise these confounds: the RED task! 🧵👇
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Excited to share this paper using new neurotech and explainable AI to advance DBS for treatment resistant #depression (TRD). Team effort including @HelenMaybergMD, @sankar_alagapan and Patricio Riva-Posse. Summary thread! go.nature.com/48lmlzC @nature PC: Mike Halerz
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Psychologists have posited hundreds of cognitive biases over the years. A fascinating new paper argues that they all boil down to one of a handful of fundamental beliefs coupled with confirmation bias. doi.org/10.1177/174569162211…
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Erik Hoel
@erikphoel17 Sep 2023
Yesterday a letter from 100 scientists declared the popular theory of consciousness - Integrated Information Theory - is "pseudoscience." And that media about it is "scientific misinformation." The letter is bad. Here's my reply why: theintrinsicperspective.com/…

Ambitious theories of consciousness are not "scientific misinformation"

In defense of Integrated Information Theory

theintrinsicperspective.com
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Attractor dynamics reflect decision confidence in macaque prefrontal cortex biorxiv.org/cgi/content/shor… #biorxiv_neursci
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YOU can help us finalize raising funds by signing in support and getting involved ➡️ BrainBehaviorObservatory.org We just held our first 🧠🌩️ Workshop at @CampusBiotech with a small yet amazing, international group 🇺🇸🇫🇷🇩🇪🇯🇵🇨🇭🇬🇧🇵🇹🇨🇾🇦🇹generously supported by @Boehringer Let's do this!
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Dopamine encoding of novelty facilitates efficient uncertainty-driven exploration biorxiv.org/cgi/content/shor… #biorxiv_neursci
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Anil Seth
@anilkseth16 Sep 2023
1/ IIT can and should be critiqued, but this letter, despite many admirable signatories (& colleagues/friends) is disappointing. The accusation of pseudoscience is serious & clickbaity & IMO the letter doesn't justify it psyarxiv.com/zsr78/

The Integrated Information Theory of Consciousness as Pseudoscience

The media, including news articles in both Nature and Science, have recently celebrated the Integrated Information Theory (IIT) as a ‘leading’ and empirically tested theory of consciousness. We are...

osf.io
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Now online in final form, work by @kt_ferguson on the role of cortical VIP interneurons in visual processing and perception! cell.com/cell-reports/fullte…

VIP interneurons regulate cortical size tuning and visual perception

Ferguson et al. show that VIP interneurons regulate cortical visual feature selectivity. Loss of VIP interneurons decreases state-dependent modulation of SST interneurons and reduces visual tuning in...

cell.com
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New paper from the lab on rule-dependent, flexible representations of sensory inputs – a decade-long journey steered by Diego Hernandez Trejo, Andrei Ciuparu and Pedro Garcia da Silva together with the Muresan lab. Follow the thread. doi.org/10.1101/2023.09.12.5…
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Excited to share this new work from @Audette_neuro! We found a prominent class of auditory cortex cells that signal prediction errors when mice hear something unexpected. 1/6
bioRxiv Neuroscience@biorxiv_neursci7 Jan 2023
Stimulus-specific prediction error neurons in mouse auditory cortex biorxiv.org/cgi/content/shor… #biorxiv_neursci
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New paper from the lab: "Sensation and expectation are embedded in mouse motor cortical activity" @BEHoley has been working to understand how motor and sensory areas exchange information during behavior. biorxiv.org/content/10.1101/…

Sensation and expectation are embedded in mouse motor cortical activity

During behavior, the motor cortex sends copies of motor-related signals to sensory cortices. It remains unclear whether these corollary discharge signals strictly encode movement or whether they also...

biorxiv.org
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