PhD Student👨🔬 🧬🦠| Microscopy 🔬💛| Sea 🌊 | Whale 🐋 Livefreeordie🍔🧢🧠🌊👓🎧👩❤️💋👨
Providencia, Chile
Joined January 2023
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PabloEsteban retweeted
SLAC congress
🗓️ April 19th-24th, 2027
📍Florianópolis 🇧🇷
🌊 🔬 📚
@SECitologia @citologiala @spcitologia @ACitopatologia @CitopatolCAT @CitologiaSac @cytopathology @IACytology @SEAP_IAP @SFCCFrance @Cytology_Uganda @Cytology_Uganda @SoDoPat @ESP_Pathology @Pathology_Xever
PabloEsteban retweeted
Se viene curso virtual para citotecnólogos junto a nuestra sociedad aliada académica @citologiala 👏🏻👏🏻
🗓️ Apunta la fecha ya en tu calendario: 20/11/25
Iremos dando más información en breve 🤓
#CursosSEC #Citologia
PabloEsteban retweeted
📣Announcing the 4th edition of the EMBL‑IBEC Conference on “Engineering Multicellular Systems”, taking place 11–13 March 2026 in Barcelona. Exploring organoids, mechanobiology, embryo models, organ-on-chip systems, multiomics and more. Abstracts open now!
events.ibecbarcelona.eu/embl…
PabloEsteban retweeted
Hoy en EMBO Life Science Forum, donde la doctora María Isabel Yuseff y los estudiantes @IsidoraRiobo , @Peaceiton y Antonia Morales presentaron los últimos descubrimientos del laboratorio.
Muchas gracias @EMBO @EMBOevents por impulsar redes colaborativas de científicos en Chile.
PabloEsteban retweeted
New research suggests that cytotoxic #Tcells’ nuclei move towards the #ImmuneSynapse to support the delivery of newly synthesized proteins during target cell killing. @TheCIMR @YaleCellBio
Learn more in Science #Immunology: scim.ag/46fhalO
PabloEsteban retweeted
🔬 Cuatro razones para unirse al IAC
Sumate a la Academia Internacional de Citología (IAC), la mayor organización profesional mundial de citopatólogos, citotecnólogos y científicos en campos afines.
¡Descubrí por qué vale la pena ser parte de la Academia! 🌍🔬
PabloEsteban retweeted
Automated optogenetic control of hundreds of cells in parallel. Each cell is individually steered, collectively acting as a "tissue printer". Preprint & code out!
PabloEsteban retweeted
Plasma Membrane Damage (0.005~0.09% SDS) induces Yeast or Fibroblast #Senescence
Activating p53-p21 axis but independently of DNA damage response
Roles of ESCRT (CHMP4B) & Glycoprotein VI
Really interested if PMD-senescence occurs in endothelial/muscle cells, or by shear/stretch, or other chemical (Digitonin), or genetical membrane injury (Dysferlin, Dystrophin)😆
Keiko Kono lab @NatureAging 2024
nature.com/articles/s43587-0…
🧡🧡🧡🧡
.@LabYuseff @uc_chile show that B cells respond to mechanical cues at the immune synapse through ATAT1-dependent microtubule acetylation to coordinate cytoskeletal dynamics & lysosome positioning, enhancing antigen extraction and presentation hubs.la/Q03y2G-f0
PabloEsteban retweeted
.@LabYuseff @uc_chile show that B cells respond to mechanical cues at the immune synapse through ATAT1-dependent microtubule acetylation to coordinate cytoskeletal dynamics & lysosome positioning, enhancing antigen extraction and presentation hubs.la/Q03y2G-f0
🧬 My first paper is out in Journal of Cell Biology! @JCellBiol
We show how B cells use ATAT1 to sense stiffness, acetylate microtubules, and improve antigen presentation.
Proud to share this milestone 🌎💪
🔗 rupress.org/jcb/article/224/…
#Bcells #Mechanobiology #Immunology #PhD
PabloEsteban retweeted
How do altered levels of lamins and other nuclear envelope proteins contribute to cancer metastasis, and how does this relate to #mechanobiology? Learn more in our recent review by @SarahHenretta now out in @Nature_NPJ - biological physics and mechanics (doi.org/10.1038/s44341-025-0…).
PabloEsteban retweeted
High-Speed Multiplexed DNA-PAINT Imaging of Nuclear Organization Using an Expanded Sequence Repertoire
Abhinav Banerjee et al.
doi.org/10.1101/2024.12.21.6…
PabloEsteban retweeted
Image: lysosomal #exocytosis occurs in the vicinity of focal adhesions. From Wei-Wei Ren, Morihisa Fujita et al. @GifuUniv_PR showing that MYO18B promotes lysosomal exocytosis by facilitating focal #adhesion maturation. hubs.la/Q03154rr0
#Lysosomes #mechanobiology
It was a great epxerience yesterday , I hope to keep talking about nucleus and actin for a long time more #ASCB2024. @LabYuseff !!
PabloEsteban retweeted
In June '24: At the moment of T cell activation, the presence, or lack, of nuclear envelope invaginations, which gather organelles, influences effector and memory fate decisions.
buff.ly/3ZzruBG
From @BenHale95, @BerendSnijder et al.
#Immunology #Tcells @ScienceMagazine
PabloEsteban retweeted
Felicitamos a @Cabrera_R_FE y @ContrerasTeemly por sus excelentes presentaciones orales en el XXXVI Congreso de @_SBCCh
Los dejamos invitados al póster de @Peaceiton que estudia la respuesta mecánica del núcleo durante la sinapsis inmune de células B
#Bcell
#Mechanobiology
PabloEsteban retweeted
#FluorescenceFriday #cellbiology #bioart A neutrophilic HL-60 cell exhibits both sheet- and rosette-like dynamic pseudopods as it migrates in 3D through a collagen mesh. Here, the cell center is marked in yellow, and each pseudopod is marked with an orange ball of size proportional to its volume. As seen by lattice light sheet microscopy.
PabloEsteban retweeted
A wonderful illustration of the different types of mechanical interactions that cells use to move collectively (and of how you can’t understand their relative contribution without force measurements). Congrats to the authors and thanks for having us on board!
How do cell interactions determine the migration of cell trains? 🦠🚂🤔
Check out our latest study in @NaturePhysics in collab w/ @GabrieleSylvain @EdouardHannezo @XavierTrepat & experiments led by @EleonoreVercru!
➡️nature.com/articles/s41567-0…