Immune regulation, regulatory T cells, inhibitory receptors, LAG3, Nrp1, IL35, cancer immunology, autoimmunity, TCR signaling

Pittsburgh, PA
Joined March 2017
Two new studies present insights into regulatory T cells located in tumors associated with head and neck squamous cell carcinomas and non-small cell #LungCancer. By @Vignali_Lab: scim.ag/46W By @SmithImmunology: scim.ag/46V
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Kicking off the #pittimm2022 departmental retreat this morning. Looking forward to some great science!
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We have to get to a point when COVID immunity is just part of our routine health care. Not an "emergency" every time there's an update. Check in with your Dr 1-2x per year. "Are you up to date w COVID vaccines?" "Any new vaccines/recommendations?" "You're due for a boost". Great.
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I am ready for #rushtocrush cancer. Join me - or better challenge me 🚴- for a great cause @RobertFerrisMD @Adrianvlee @Vignali_Lab @KMBaileylab @airdlab @OveracreLab @Adrianvlee @RobertFerrisMD @neil_carleton_ @cyndypatton @NadineHempel #r2c – at Fox Chapel, PA
Dr. Steffi Oesterreich crushes cancer through her research. 🔬⚙️ Learn more about her work here: rushtocrushcancer.org/storie… We're just FOUR days away from registration opening. 🎉How will you get involved? #r2c #rushtocrush
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Vignali Lab retweeted
A great example of translating scientific discovery into commercial opportunity! @UPMCHillmanCC @UPMCEnterprises
Novasenta, a @UPMCEnterprises portfolio company founded by @RobertFerrisMD, @DelgoffeLab, and @Vignali_Lab of @UPMCHillmanCC, announced today the completion of a $40M Series A financing. enterprises.upmc.com/blog/no…
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Exclusive: UPMC launches another biotech, rooted in the tumor microenvironment - More like this Pharm2Market.app | @Vignali_Lab @DelgoffeLab @RobertFerrisMD #novasenta #Financing #Startups #Cancer #Therapeutics #Tumor #Bitoech endpts.com/exclusive-upmc-la…
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Vignali Lab retweeted
Vignali Lab is recruiting post-docs! Please see below for details.
Congratulations to Drs. Tullia Bruno (@BcellBruno) and Jason Luke (@jasonlukemd) from @UPMCHillmanCC as newly-elected @sitcancer at-large directors!
We are pleased to announce the results of the 2022 SITC Election. These leaders are ready to contribute to the society's bright future beginning in January 2023. A big thank you to this year’s candidates and voters! View results: sitcancer.org/membership/202… #MakingCureaReality
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Looking for a post-doc and wanna fight #tuberculosis? The Barber lab at the NIH in Bethesda, MD is looking for post-doctoral fellows to work on T cell responses to M. tuberculosis infection. Check us out. The NIAID Division of Intramural Research is an amazing place to train!
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Congratulations to Paolo Vignali @pdaVignali and your outstanding thesis defense presentation and work on targetable immunosuppression in the TME mentored beautifully by Greg Delgoffe @gmdelgoffe @DelgoffeLab @UPMCHillmanCC
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Today we're proud to announce a new event called Rush to Crush Cancer (@R2C_Cancer). It's a bike ride coming in the summer of 2023 with a goal of raising critical funds to support groundbreaking #CancerResearch! rushtocrushcancer.org/ @bwild1842 @RobertFerrisMD @RUNwithP3R
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Partner. Give. Volunteer. Learn how to get involved: rushtocrushcancer.org/get-in… #RushToCrush #R2C
#OnlineFirst: Systemic immune dysfunction in cancer patients driven by IL6 induction of LAG3 in peripheral CD8+ T cells. Study by Somasundaram, Bruno, Vignali et al. bit.ly/3wPGNrp @jmkirkwood, @evanlipson, @Vignali_Lab, @BcellBruno
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Vignali Lab retweeted
Looks like Pittsburgh is objectively the best place to do your postdoc
New paper “American postdoctoral salaries do not account for growing disparities in cost of living” I found that real postdoc salaries vary by ~ 29% ($15k) depending on where you live (and your university) arxiv.org/abs/2205.12892
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I’m very excited to share my first, first author research paper with @Sherry_ZhangQZ! @Vignali_Lab @NatImmunol nature.com/articles/s41590-0…
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Don’t forget to vote by this Friday if you are a SITC member!!
The future is bright at SITC! Get to know 2022 SITC At-Large Director candidate, Tullia Bruno, PhD (University of Pittsburgh). Read Dr. Bruno’s bio and position statement: sitcancer.org/membership/202…
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New study by @UPMCHillmanCC immunologist, Dr. Dario Vignali (@Vignali_Lab) on how LAG3 works, published today in @NatImmunol. The findings could lead to new therapies for #Cancer & autoimmune disorders. upmc.com/media/news/041922-i… @UPMCnews @UPMCPhysicianEd @PittHealthSci
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Researchers id peripheral blood transcriptional profiles associated with mortality in critically ill COVID-19 pts. SARS-CoV-2-infected macrophages in lung express high levels of CXCL10 @tonyrcillo @KitsiosMd @BcellBruno @Vignali_Lab

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