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JUST IN: UC Berkeley math professor stops grading homework for correctness, saying widespread AI use has made it "pointless," and now awards credit simply for turning in assignments.
$TNGX hilarious price action to highly durable ~80% response rate in 2L PDAC.
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For the first time in history, nearly 60% of the S&P 500’s components are in a bear market, while the index trades 3% away from a record high.
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Unlike the dot-com bubble, when global technology stocks surged far ahead of earnings, the current rally has been supported by stronger earnings growth.
Source: @steve_donze
$PFE BD should take a good look at this
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Can u imagine . Not a single word or line about perioperative pembrolizumab use for presidential abstract discussion about melanoma in 2026 @myESMO .
Are u amazed ? @dr_yakupergun @DrYukselUrun @OncBrothers @JacobPlieth
Love PRMT5. Incredible durability (better than ADCs). $TNGX will get picked up soon IMO.
Room for multiple players. BeOne $BMY
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Three legit candidates for a standing ovation at the Esmo presidential this afternoon: Interpath, Volga and Dellphi
JUST IN: DeLLphi-305: Small Cell Lung Cancer Extensive-Stage
Phase III (n=563): Tarlatamab + Durvalumab vs Durvalumab as 1L maintenance after chemo-IO, to be presented by our own @sands_jacob from @DanaFarber
• Median OS: 21.1 vs 12.7 months (HR 0.42)
• Median PFS: 7.4 vs 1.9 months (HR 0.34)
• ORR: 26.4% vs 4.1%
Grade ≥3 AEs: 46.8% vs 40.6%; CRS 49.6% (most low grade).
Probably new standard of care in ES-SCLC.
@OncoAlert @DanaFarberNews #ESMO26
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Another interstitial lung disease death raises more deruxtecan doubts - this time with ralu-dxd plus Avastin at #ESMO26. The @ApexOnco take apexonco.com/esmo-2026-anoth…
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PD-(L)1 blockade has made inroads into triple-negative breast cancer, but ER+/Her2- space is still a no go, judging by $MRK flop in Keynote-B49. From #Esmo26 via @ApexOnco -> apexonco.com/esmo-2026-keytr…
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BMS has reported a new autoimmune CAR-T death, that it says look unrelated to its ICANS cases or Novartis' IEC-HS deaths that led the companies to pause their trials this summer $BMY
My story for @endpts:
endpoints.news/bristol-myers…
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Tango reports 82% tumor response rate in trial of combo therapy (Daraxonrasib plus vopimetostat) for advanced #PancreaticCancer at #ESMO26
statnews.com/2026/10/23/esmo…
Reduced toxicity data is particularly important as a lower Daraxonrasib dose can be used.
$TNGX the PFS curve for 2L PDAC is 🔥
$TNGX data is out :
1- 82% ORR
2- 88.4% 6mo and 9mo landmark PFS (from 90% in June) (100% in 2L)
3- Safety similar rates of low Gr rash, stomatitis/mucositis, and diarrhea as previously reported
tangotx.com/wp-content/uploa…
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$IDYA IDE849 (SHR-4849) DLL3 TOP1 ADC Updated Phase 1 Results at ESMO 2026 Demonstrates Promising Anti-Tumor Activity and Preliminary Overall Survival Results in Relapsed Small Cell Lung Cancer and Neuroendocrine Carcinomas - Oct 23, 2026 media.ideayabio.com/2026-10-…


























