Associate Professor of Nephrology @IcahnMountSinai on BlueSky: https://teapawt.net/t.co/thJDJUsz4U
New York, NY
Joined July 2010
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Happy to share the first set of integrated results from our reference tissue atlas effort from Kidney Precision Medicine Project consortium @KPMProject out yesterday on @ScienceAdvances. 🧵 (1/4)
science.org/doi/10.1126/scia…
Evren U. Azeloglu retweeted
Super pleased to see this paper officially published! @azeloglu visited the @AICjanelia back in the spring of 2022 to use the MOSAIC and was able to generate some nice data to contribute to this piece.
Read more here: science.org/doi/10.1126/scia…
Evren U. Azeloglu retweeted
The renal immune infiltrate observed in autosomal polycystic kidney disease contributes to the evolution of the disease. This study found activation of the cGAS/STING pathway contributes to ADPKD cystogenesis bit.ly/JASN0305
@azeloglu
ALT Visual Abstract for the article titled "cGAS Activation Accelerates the Progression of Autosomal Dominant Polycystic Kidney Disease"
Evren U. Azeloglu retweeted
3 of our nephrologists @azeloglu @DMohottige @LilCh4n discuss their #kidney research here on: health care disparities, #AI, & innovations in the lab
youtube.com/watch?v=dfFzxBjT…
@DOMSinaiNYC @IcahnMountSinai #Nephrology
Evren U. Azeloglu retweeted
Open-Source System for Real-Time Functional Assessment of In Vitro Filtration Barriers @IcahnMountSinai @EE_ColumbiaSEAS @azeloglu @BMESociety @SpringerNature
Link: rdcu.be/dzwaM
Evren U. Azeloglu retweeted
Dasatinib has been linked to nephrotoxicity. In this Podcast, Drs Benjamin Adegbite & @azeloglu discuss their findings that exposure to dasatinib was linked to a significant chance of developing proteinuria compared with similar tyrosine-kinase inhibitors bit.ly/CPOD0219
ALT Visual Abstract for the article titled "Patient-Specific Pharmacokinetics and Dasatinib Nephrotoxicity"
Evren U. Azeloglu retweeted
Next up Dr. Alan Stern:
"A biomimetic culture & machine vision system for drug discovery"
@ISMMSKidney @azeloglu @IcahnMountSinai
#Nephrology #Research
I’ve been meaning to announce this for awhile, but the irony of tweeting out my female trainees’ successes while they are being robbed of their basic human rights was too much to handle.
Tess, was among the first all-women class of MERRIT fellows last summer. In her spare time from being one of the top (and select female) electrical engineering students at Columbia, she continued her project with us. And clearly did an awesome job.
Albeit with some delay, help me congratulate our lab’s first MERRIT Fellow, Tess Fallon, for winning the SB3C student paper competition!
ALT 2022 SB2C Student Paper Competition First Place Certificate for Tess Fallon
ALT Tell Fallon
Evren U. Azeloglu retweeted
*The human kidney atlas*
A new atlas called the Kidney Precision Medicine Project, constructed by researchers @IcahnMountSinai, @Princeton, @FlatironInst & @umichmedicine just dropped.
1/
Thank you all MERRIT Mentors for your commitment to educating the next generation of physicians and scientists that will help end #kidneydisease.
This year’s all-women fellowship class is the top of their respective classes. @womeninnephro
They will work on all sorts of amazing stuff, from quantitative fluorescent lifetime analytics to ML-based renal digital pathology to racial disparities in healthcare.
MERRIT is a NIDDK-supported summer undergraduate fellowship program run by @ISMMSKidney and @cooperunion. We recruit the best and the brightest engineering students to solve some of the most challenging problems in #nephrology.
This was obviously a gargantuan team effort, with co-authors from 15 international institutions. And I’m honored to have co-led the publication with Drs. Kretzler, Iyengar and Troyanskaya. (4/4)
Our integrated analysis was able to reconstruct the subsegmental physiological activity for each cell type along the human nephron.
And it will form the backbone of @KPMProject’s vision to reclassify and cure #kidneydisease. (3/4)
We harmonized data from multiple transcriptomics, proteomics, metabolomics and imaging assays to construct a human kidney tissue atlas at the single-cell resolution.
All of it can be viewed through our open-access kidney tissue atlas here: atlas.kpmp.org (2/4)
ALT “Subway Map” outline of our data integration pipeline.