European Commission sounds the alarm (now !!!) about the number of oil refineries closing in the region over the last 20 years. "We need to counter this trend," says EU Energy Commissioner Dan Jørgensen. "This crisis is a wake-up call." Quite.

BREAKING: A BALLISTIC MISSILE JUST LANDED AT ADEN AIRPORT. 15 minutes later the Houthis told everyone there to leave. Now. Their reason: a "Saudi military cargo plane" loaded with weapons. Not a stray shot. A named Saudi target, announced in advance. Is Aden the next front?

🇪🇸 Spain records at least five fatal high-speed rail accidents in 2026 1) Adamuz rail disaster (January 18) A high-speed Iryo train derailed in Adamuz (Córdoba) on the Madrid–Seville line after a fractured rail weld. Seconds later, a southbound Renfe train slammed into the derailed carriages, killing 46 and injuring 292. 2) Gelida train derailment (January 20) Commuter train hit a collapsed wall damaged by Storm Harry. Trainee driver killed, at least 37 injured. 3) Cartagena train accident (January 22) A passenger train in Cartagena collided with a crane arm on the tracks. Six people were injured. No fatalities. 4) Talavera la Real accident (February 12) Another rail incident in Talavera la Real added further pressure on infrastructure manager Adif. 5) Toledo high-speed collision (October 28) Today’s rear-end collision between an Iryo and a Renfe train on the Madrid-Andalusia line in Toledo has left at least 39 dead and shut down major southbound traffic. At least 86 were killed across the five accidents. Earlier incidents alone injured at least 335 people. Today’s Toledo crash happened on the same line as the January 18 Adamuz disaster. Video from the scene of the deadly Toledo rail collision

Jamie Dimon to a country that pulled its gold out of New York: you have three armies within 400 miles, while gold in America is protected by two oceans and the US military “If we have the strongest military in the world and the strongest economy in the world, we will be the preeminent reserve currency. It is those two things.” “I was in a country somewhere in the Middle East, and also in Europe, and the people said, we took our gold out of the vaults in New York City and moved it to our country. You know what I said to him? I said, you have three armies within 400 miles who can come take your gold.” “That’s the real world. You’re not thinking clearly about safety. That gold is protected by the Atlantic, the Pacific, the United States military, the rule of law.” “But if we are not the preeminent military and economy, you will see our reserve status come down.”

I'll leave this here. It should explain the cognitive dissonance...

Anthropic's is officially steering internal models and compute on solving drug discovery with the goal of solving all rare and common diseases, progress so far is v impressive: - acquired a 1-person medicine startup that created 2 potential treatments for muscular dystrophy (in 18 months!) - on multiple occassions claude not only designed but selected drug designs that ended up testing better than the current cure. insane. - claude cut paperwork down 89% freeing up staff to focus on real research. this saves millions of dollars at scale in big pharma. all of these are pre-clinical now but just imagine where we are 6 months from now when more science labs have access to better models?

Golden words by @nc_frey - something I've been preaching for the past 3 years. Scaling drug discovery in many areas is the only way to learn. But what really matters is the quality of the program and depth of the data room. At Insilico, we now have 40+ programs with 35 programs past PCC/DC with deep data and even novel mechanisms (eg novel antipain.ai drug) - these are the most valuable data sets and experience in the galaxy. Quality is usually assessed when the pharma buys your drug or when it goes Phase 2/3. You need to sell/progress a few to know how well it works. We are working on a set of tools on Grok Bot that will allow you to go end-to-end for program-level reasoning. And xPharma.ai lead by @sastrycvs, David Berry and others is specializing in end-to-end data rooms. IMHO, frontier labs will be acquiring productive biotech companies at scale in near future. Many of these companies are in China and many need the regulatory approvals to sell so it will be interesting to see how they do it. The biggest frontier AI battle will be in pharma as it is the highest-value and most difficult area of human development. Half-baked scorpion antivenoms make great demos but do not make great drugs. Watch this space as it evolves - it will have a profound effect on your life. In the West, the champions will be @SpaceX and @AnthropicAI and in the East, it will likely be @TencentHunyuan and @Alibaba_Qwen . In the Middle East, it will be @InSilicoMeds . And in Europe... many people will benefit in Europe.

⚡️Putin lectured Nordic leaders on Russian history during latest call, FT reports. kyivindependent.com/putin-le…

Asian-Americans in Harvard’s Incoming Class More Than Double, to 43.2 Percent Newly released data on the Harvard College class of 2030 say the class is 43.2 percent Asian-American, a record high and more than double the level when Students for Fair Admissions first sued Harvard alleging racial discrimination in admissions. The U.S. Supreme Court ruled in 2023 that Harvard was unlawfully using race as a factor in admissions. Since then, the numbers of Hispanic and black students in the incoming Harvard classes have dipped, while the numbers of Asian-Americans have soared.

⭕️ BREAKING: Prime Minister Benjamin Netanyahu’s right-wing coalition is projected to fall from 68 seats in the outgoing Knesset to 52, according to the latest updated Channel 12 exit polls and voting results cited by CNN. ➤ Netanyahu bloc (still in the lead): 52 seats ➤ Gadi Eisenkot-led opposition (early projections had him higher than Netanyahu’s bloc): 49 seats ➤ Palestinian parties: 19 seats, potentially record representation Neither major bloc has secured the 61 seats needed for a majority, following Israel’s highest voter turnout since 1999. Palestinian-led parties could prove decisive in determining the next government. A minority government, unity coalition, or another election are all possible. Final results are pending, with coalition negotiations potentially lasting weeks. Chart: CNN

golden. #richestcountry etc. carry on 😂

A Chinese company uses civil unrest in France as an ad to promote the durability of its glass.

Ben Scallan reacts to an absurd story from Longford District Court regarding Irish citizenship which "actually beggars belief".

🇩🇰 Danish PM Mette Frederiksen criticized the Finnish and Norwegian leaders’ call with Putin, saying she was “very skeptical” of the initiative and questioning what they hoped to achieve.

⚡️️ 302,000 Russian soldiers killed or wounded by Ukrainian drones since January, Defense Ministry says. The highest number of casualties Ukrainian drones inflicted on the Russian military was recorded in March, with almost 34,000 soldiers killed or irrecoverably wounded. kyivindependent.com/302-000-…