Sebastian Garzon

Correlation between second and first primary cancer: systematic review and meta-analysis of 9 million cancer patients ➡️ doi.org/10.1093/bjs/znad377 This study is the first to use a meta-cohort of 726 019 patients with second primary cancer (SPC), incorporating up to 28 human organs as first primary cancer (FPC) sites to perform a systematic and pan-cancerous study of the possible correlation between SPCs and FPCs. We found multiple epidemiological clusters of organs of FPCs: 1⃣FPCs of the uterus, ovary, thyroid, fallopian tube, vulva and vagina are more likely to develop into SPCs of the breast and colorectum 2⃣second primary lung cancer is more frequently developed in patients with FPCs of the head and neck, anus and oesophagus 3⃣FPCs of the bladder and penis are more likely to develop into second primary prostate cancer and lung cancer 4⃣among patients who had an FPC in the ureter and developed an SPC, the rate of second primary bladder cancer was as high as 56%. We recommend close clinical follow-up, monitoring and appropriate interventions in patients with relevant FPCs for better screening and early diagnosis of SPCs to prolong patient survival. Great work by Xinyu Wang, Meiyuan Zeng, Xueming Ju, Anqi Lin, Chaozheng Zhou, Junyi Shen, Zaoqu Liu, Bufu Tang, Quan Cheng, Youyu Wang, Jian Zhang, Peng Luo #SoMe4Surgery #MedTwitter #SurgEd #Surgery #systematicreview @RCPSGTrainees @BJSAcademy @BjsOpen @young_bjs @escp_tweets @asgbi