cancer immunology - sarcoma - melanoma - radiation oncology - https://xitter.cf/t.co/ZhHn8j94Nm @stanford

Los Angeles, CA
Joined May 2012
Anusha Kalbasi retweeted
Excited to share our new study describing uRARE-seq, a tumor-naive #LiquidBiopsy method for analyzing urine cell-free RNA (cfRNA) in #BladderCancer and other genitourinary cancers. Out today in @NatureMedicine 🧵 1/16 rdcu.be/bRoXk7REWtRa
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Soft tissue sarcomas (#STS) have few recurrent mutations, making ctDNA testing a challenge. In our new paper in @JCO_ASCO, we show that personalized ctDNA analysis achieves high detection rates and can track treatment response in localized STS. 🧵 (1/11) doi.org/10.1200/JCO-26-00769
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Way to go Kayla, so well-deserved!
Feeling incredibly thankful to be awarded an NIH F30 Fellowship to continue my PhD work in cancer immunology. And grateful for my PI @xrtcell and my amazing lab for their support!
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Anusha Kalbasi retweeted
Highly anticipated data with first in class modified TIL therapy that does not use IL2, has lower dose lymphodepleting chemo - single arm ph1/2 OBX-115 in refractory metastatic melanoma #ASCO26 @DrBetofMDPhD @StanfordCancer ORR 67% w 2 CR (!!) DoR not reached (1+ to 14+m)
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SCI member @xrtcell & others show that combining targeted #RadiationTherapy with an experimental immune-boosting drug (BO-112) & anti-PD-1 therapy before surgery may help the immune system fight aggressive #SoftTissueSarcomas. brnw.ch/21x2SeG
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Anusha Kalbasi retweeted
🚨What if we could reliably program macrophage polarization state?🚨 biorxiv.org/content/10.64898… Macrophages are highly plastic immune cells that perform critical functions by polarizing into distinct cellular states. The polarization state of macrophages can substantially influences the progression of cancers, infections, and autoimmunity. (1/11)
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If you haven’t REAP’d, have you really lived?
Autoantibodies cause autoimmune disease, shape infection outcomes, and alter cancer immunotherapy. But what role might they play in neuropsychiatric disease? In our new preprint, Katlyn Nemani and @JillianRJaycox take on this question in schizophrenia. 🧵 biorxiv.org/content/10.64898…
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Radiation is a powerful anti-cancer agent, but I considered it a weak immunomodulator. Our new study @CD_AACR changed my mind: in the right context, RT can incite potent systemic immune responses in patients (even rare irAEs). Which context? brnw.ch/21x1b6E A 🧵 /1
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Congrats to first author @JieDeng (my first post-doc, now leading her own group), UCLA Sarcoma program, and our @StanfordMed team on rich correlatives (@AasthaPal @Stef_Tst @ZinaGood @aaronmring @everettmoding) /9
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Made possible by Marisol Quintero & team @Highlight_HLT, @theNCI, @StanfordCancer, @ConquerCancerFd, @UCLAJCCC. And most importantly, our patients. /10
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Thrilled to share the primary focus of my PhD thesis work, now out in @ScienceMagazine today! We developed Trikines — engineered cytokines that reconfigure receptor complex assembly to reshape signaling directly in endogenous immune cells. doi.org/10.1126/science.adx9…
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thanks @JoeFraietta and Janna for having me on!
In our latest episode of #ImmunoLogic, the hosts spoke with Anusha Kalbasi, MD (@xrtcell, @stanford) about his research on IL-9 and CAR-T #Oncology #Immunotherapy @PennMedicine @JoeFraietta Watch now: hubs.li/Q03WB7TD0
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